List of Famous people born in Ōsaka Prefecture, Japan

Seiji Tomashino is a Japanese former Nippon Professional Baseball infielder/outfielder.

Rome Kanda is a Japanese tarento, comedian and actor who resides in the United States. He currently lives and works in Los Angeles, California.

Ryang Yong-gi is a Japanese-born North Korean footballer who plays for Sagan Tosu in the J1 League.

Shinya Yamada , better known exclusively by his stage name Shinya (真矢), is a Japanese musician, media personality and entrepreneur. He is best known as the drummer of the rock band Luna Sea since 1989.

Dairyū Tadahiro is a former sumo wrestler from Osaka, Japan. He made his professional debut in May 1976, but never reached the top division. His highest rank was jūryō 4, which he reached in January 1990. He retired in July 1997 and became an elder in the Japan Sumo Association. He assumed the role of head coach of Ōtake stable in July 2010, shortly after former head coach (ex-sekiwake) Takatōriki was fired by the Sumo Association for betting illegally on baseball.

Ryuhei Kitamura is a Japanese filmmaker.

Takuji Yanagimoto is a Japanese politician of the Liberal Democratic Party (LDP), a member of the House of Representatives in the Diet. A native of Osaka, Osaka, he attended Waseda University as a graduate student. He was elected to the first of his three terms in the city assembly of Osaka in 1975. After running unsuccessfully for the House of Representatives in 1986 as an independent, he ran again in 1990 as a member of the LDP and was elected for the first time.

Sanae Tsuchida is a Japanese actress. She was born on July 26, 1949, in Toyonaka, Osaka.

Lucas Tsuyoshi Honda is a Japanese figure skater. He is the 2020 NHK Trophy bronze medalist and the 2020–21 Japan junior national champion.