List of Famous people born in Novo Mesto, Slovenia

Melania Trump is a Slovene-American former model and businesswoman. She was the first lady of the United States from 2017 to 2021, during the presidency of her husband, Donald Trump.

Edvard Ravnikar was a Slovenian architect.

Primož Kozmus is a Slovenian hammer thrower. His gold medals in the 2008 Summer Olympics in Beijing and the 2009 World Championships in Berlin made him the first ever Slovenian athlete to win both titles.

Blaž Jarc is a Slovenian former professional cyclist, who competed professionally between 2007 and 2014.

Branko Filip is a former Slovenian cyclist he is current coach of the men's cycling team Torku Şekerspor of Turkey.

Martin Derganc is a Slovenian former professional road cyclist.

Igor Lukšič is a Slovenian political scientist, politician and was president of the Slovenian Social Democrats. Between November 2008 and February 2012, he served as Minister of Education in the center-left government of Borut Pahor.

Marko Kump is a Slovenian former professional cyclist, who rode professionally between 2007 and 2020 for the Geox–TMC, Tinkoff–Saxo, UAE Team Emirates and CCC–Sprandi–Polkowice teams, as well as four separate spells with the Adria Mobil team. He now works a directeur sportif for the Adria Mobil team, a UCI Continental team.

Gorazd Štangelj is a Slovenian former professional road bicycle racer, who raced as a professional between 1997 and 2011. He currently works as a directeur sportif for UCI WorldTeam Team Bahrain Victorious.