List of Famous people born in Missouri, United States of America

Edwin Powell Hubble was an American astronomer. He played a crucial role in establishing the fields of extragalactic astronomy and observational cosmology.

Mircea Monroe is an American model and actress, known for her roles on the TV series Episodes as Morning Randolph (2011–2017), Hart of Dixie as Tansy Truitt (2011–2015), Impastor as Alexa Cummings (2015–2016) and Sing It! as Stacey Needles (2016). She has also performed in films including Cellular (2004), House of the Dead 2 (2005), Just Friends (2005), The Change-Up (2011) and Magic Mike (2012).

Donald Frank Cheadle Jr. is an American actor, author, director, producer and writer. Following early roles in Hamburger Hill (1987), and as the gangster "Rocket" in the film Colors (1988), Cheadle built his career in the 1990s with roles in Devil in a Blue Dress (1995), Rebound: The Legend of Earl 'The Goat' Manigault (1996), Rosewood (1997), and Boogie Nights (1997). His collaboration with director Steven Soderbergh resulted in the films Out of Sight (1998), Traffic (2000), and The Ocean's Trilogy (2001–2007).

Aliaune Damala Badara Akon Thiam, also known mononymously as Akon, is a Senegalese-American singer, rapper, songwriter, record producer, entrepreneur, philanthropist, and actor from New Jersey. He rose to prominence in 2004 following the release of "Locked Up", the first single from his debut album Trouble (2004), followed by the second single "Lonely."

Carlos Roberto PeñaVega is an American actor and singer. He starred on the Nickelodeon series Big Time Rush as Carlos García, and was a member of the band Big Time Rush. He was also the host of the network's game show Webheads.

Sophie Cunningham is an American professional basketball player for the Phoenix Mercury of the Women’s National Basketball Association (WNBA).

Leon Spinks is an American former professional boxer who competed from 1977 to 1995. In only his eighth professional fight, he won the undisputed heavyweight championship in 1978 after defeating Muhammad Ali in a split decision, in what was considered one of the biggest upsets in boxing history. Spinks was later stripped of the WBC title for facing Ali in an unapproved rematch seven months later, which he lost by unanimous decision.

Richard Claxton Gregory was an American comedian, civil rights and vegetarian activist. His writings were best sellers. Gregory became popular among the African-American communities in the southern United States with his "no-holds-barred" sets, poking fun at the bigotry and racism in the United States. In 1961 he became a staple in the comedy clubs, appeared on television, and released comedy record albums.

Jane Wyman was an American actress, singer, dancer, and philanthropist. She received an Academy Award, three Golden Globe Awards and nominations for two Primetime Emmy Awards.

Dorothy Johnson Vaughan was an American mathematician and human computer who worked for the National Advisory Committee for Aeronautics (NACA), and NASA, at Langley Research Center in Hampton, Virginia. In 1949, she became acting supervisor of the West Area Computers, the first African-American woman to supervise a group of staff at the center.