List of Famous people born in León, Mexico

Columba Bush ; née Garnica Gallo; born August 17, 1953) is a Mexican-American philanthropist. Bush served as First Lady of Florida from 1999 to 2007 and is the wife of former Florida Governor Jeb Bush.

Vicente Fox Quesada GCMG CYC is a Mexican businessman and politician who served as the 62nd President of Mexico from 1 December 2000 to 30 November 2006.

María Grever was the first female Mexican composer to achieve international acclaim. She is best known for the song "What A Difference A Day Makes", which was popularized by Dinah Washington and has been covered by numerous artists.

José Ulises Macías Salcedo, Archbishop emeritus of the Archdiocese of Hermosillo, was born in León, Guanajuato, Mexico, on October 29, 1940.

Juan Pablo Magallanes Aranda is a Mexican cyclist.

Lucía Leticia Méndez Pérez is a Mexican telenovela and film actress, top model and singer. Méndez was born January 26, 1955 in León, Guanajuato, Mexico.

Renato Ascencio León was a Mexican Catholic prelate. He was territorial prelate of the Diocese of Madera from 1988 to 1994 and the Bishop of Ciudad Juárez from 1994 to 2014.

Carlos Medina Plascencia is a Mexican politician affiliated with the conservative National Action Party (PAN). He is a former mayor of León, senator and interim governor of Guanajuato. He was the President of the Chamber of Deputies in 1999. In 2005 he ran for president of the PAN but lost against Manuel Espino.