List of Famous people born in Istanbul, Istanbul Province

Constantine VII Flavius Porphyrogenitus was the fourth Emperor of the Macedonian dynasty of the Byzantine Empire, reigning from 6 June 913 to 9 November 959. He was the son of Emperor Leo VI and his fourth wife, Zoe Karbonopsina, and the nephew of his predecessor Emperor Alexander.

Koca Mustafa Reşid Pasha was an Ottoman statesman and diplomat, known best as the chief architect behind the Ottoman government reforms known as Tanzimat.

Theodore II Palaiologos or Palaeologus was Despot in the Morea from 1407 to 1443 and in Selymbria from then until his death.

Konstantios Doukas, Latinized as Constantius Ducas, was a junior Byzantine emperor from 1060–1078, and a senior Byzantine emperor for a short time in 1078. Konstantios was the son of Emperor Constantine X Doukas and Empress Eudokia Makrembolitissa. Upon his birth, he was elevated to junior emperor, along with his brother Michael VII. He remained as junior emperor during the reigns of Constantine, Romanos IV Diogenes, and Michael VII, before he became senior emperor on 31 March 1078, due to the abdication of Michael VII. He was soon handed over to Nikephoros III, a usurper, due to his inability to rule. He was sent to live in a monastery, where he stayed until recalled by Alexios I Komnenos, who made him a general. He was killed on 18 October 1081, in the Battle of Dyrrhachium.

Theodora Kantakouzene Megale Komnene was the Empress consort of Alexios IV of Trebizond. Said to be very beautiful, according to the chronicle of Laonikos Chalkokondyles, she was accused by her son, John Megas Komnenos, of having an affair with the protovestiarios of the court of Trebizond; however, other accounts describe her as a faithful and loving wife, who kept the peace between Alexios and his sons. In either case, during her lifetime their son John fled to Georgia and did not return until after Theodora's death.

Flavius Stilicho or Stilico was a military commander in the Roman army who, for a time, became the most powerful man in the Western Roman Empire. He was of Vandal origins and married to Serena, the niece of emperor Theodosius I, and became guardian for the underage Honorius. After many years of victories against a number of enemies, both barbarian and Roman, a series of political and military disasters finally allowed his enemies in the court of Honorius to remove him from power, culminating in his arrest and subsequent execution in 408.

Simonida Nemanjić, born Simonis Palaiologina, was a Byzantine princess and queen consort of the Kingdom of Serbia, wife of Serbian king Stefan Milutin. Queen Simonida was a daughter of the Byzantine Emperor Andronikos II Palaiologos and Irene of Montferrat. In Medieval Serbia Queen Simonida is best remembered as a patron of Fine Arts, Arts and Letters.

Mehmet Recep Peker was a Turkish military officer and politician. He served in various ministerial posts and finally as the Prime Minister of Turkey.

Marcia Euphemia was the wife of Anthemius, Western Roman Emperor.

Theodora Angelina was the wife of Leopold VI of Austria, by whom she had several children. As a child, she was used by her grandfather, Emperor Alexios III Angelos, as a political tool to gain the allegiance of the regional strongmen Ivanko and Dobromir Chrysos. Her betrothals or marriages to them were cut short as both were successively captured by the Emperor.