List of Famous people born in Guayas Province, Ecuador

Erick Steven Ferigra Burnham is an Ecuadorean professional footballer who plays as a centre-back for Italian club Torino.

Luis Alberto "Kunty" Caicedo Medina is an Ecuadorian footballer who plays as a central defender for club L.D.U. Quito.

Andersson Rafael Ordóñez Valdéz is an Ecuadorian footballer who plays as a centre-back for L.D.U. Quito.

María Alejandra Muñoz Seminario is an Ecuadorian politician and lawyer currently serving as Vice President of Ecuador since 2020. She is the third female to hold this position, after Rosalía Arteaga and Maria Alejandra Vicuña.

Michael Craig Judge is an American animator, actor, voice artist, writer, filmmaker and musician. He is the creator of the animated television series Beavis and Butt-Head, and co-creator of the television series King of the Hill (1997–2010), The Goode Family (2009), Silicon Valley (2014–2019), and Mike Judge Presents: Tales from the Tour Bus (2017–2018). He also wrote and directed the films Beavis and Butt-Head Do America (1996), Office Space (1999), Idiocracy (2006), and Extract (2009).

Joao Jimmy Plata Cotera is an Ecuadorian footballer who plays for Liga MX club Toluca as a forward.

Maximilian Barreiro is an Argentine forward who plays for Ecuadorian Serie A side Aucas.

Jorge David Glas Espinel is an Ecuadorian politician and electrical engineer. He served as Vice President of Ecuador from 24 May 2013 – 13 December 2017. President Lenín Moreno suspended Glas of his official duties as Vice President on 3 August 2017. In December 2017, Glas was sentenced to six years imprisonment by a Criminal Tribunal of the National Court of Justice, for receiving over $13.5 million in bribes in the Odebrecht scandal.

Luis Alfredo Palacio González is an Ecuadorian cardiologist and former politician who served as President of Ecuador from April 20, 2005 to January 15, 2007. From January 15, 2003 to April 20, 2005, he served as vice president, after which he was appointed to the presidency when the Ecuadorian Congress removed President Lucio Gutiérrez from power following a week of growing unrest with his government.