List of Famous people born in Guayas Province, Ecuador

Leonardo Campana Romero is an Ecuadorian professional footballer who plays as a forward for Portuguese club Famalicão, on loan from Wolverhampton Wanderers, and the Ecuador national team.

Abdalá Jaime Bucaram Ortiz is an Ecuadorian politician and lawyer who was President of Ecuador from August 10, 1996, to February 6, 1997. As President, Abdalá Bucaram was nicknamed "El Loco Que Ama" and was removed from office after being declared mentally unfit to rule by the National Congress of Ecuador on February 12, 1997. Bucaram claims innocence now that all cases against him have been dismissed. He lived in exile in Panama under Political Asylum laws, then returned to Ecuador in 2017 when the charges against him expired.

Cynthia Fernanda Viteri Jiménez de Villamar is an Ecuadorian lawyer, journalist and politician. On March 24, 2019, she was elected Mayor of Guayaquil, the largest city in Ecuador, in the sectional elections of Ecuador for a term from May 14, 2019 until May 14, 2024. She was the presidential candidate for Partido Social Cristiano in the 2017 presidential elections, and was a candidate in the 2006 presidential elections of Ecuador and finished fifth. Between 1998 and 2007 she was a member of the National Congress. In 2009 she became a member of the National Assembly.

Roberto Manrique is an Ecuadorian model, and actor best known for his roles in telenovelas. Starting his career in Ecuador, and later doing telenovelas for Telemundo Network in Colombia.

Christian Fernando Noboa Tello is an Ecuadorian footballer who plays for Russian Premier League club PFC Sochi and the Ecuadorian national team as a central midfielder.

Joao Robin Rojas Mendoza is an Ecuadorian professional footballer who plays as a right winger for Orense. He also holds Mexican citizenship.

Michael Steveen Estrada Martínez is an Ecuadorian professional footballer who plays for Liga MX club Toluca and the Ecuador national team as a forward.

Michael Antonio Arroyo Mina is an Ecuadorian footballer who plays for Barcelona SC of the Ecuadorian Serie A, and the Ecuadorian national team as an attacking midfielder.

María Alejandra Vicuña Muñoz is an Ecuadorean politician who served as the Vice President of Ecuador under President Lenin Moreno between January and December 2018, previously as the Housing and Urban Development Minister of Ecuador.

María Gabriela Pazmiño Pino, nicknamed Gaby, is an Ecuadorian television presenter, cheerleader, dancer, and politician. She is married to Abdalá Bucaram Jr., with whom she has had four children.