List of Famous people born in East Macedonia and Thrace, Greece

Ibrahim Pasha was the eldest son of Muhammad Ali, the Wāli and unrecognised Khedive of Egypt and Sudan. He served as a general in the Egyptian army that his father established during his reign, taking his first command of Egyptian forces when he was merely a teenager. In the final year of his life, he succeeded his still living father as ruler of Egypt and Sudan, due to the latter's ill health. His rule also extended over the other dominions that his father had brought under Egyptian rule, namely Syria, Hejaz, Morea, Thasos, and Crete. Ibrahim pre-deceased his father, dying 10 November 1848, only four months after acceding to the throne. Upon his father's death the following year, the Egyptian throne passed to Ibrahim's nephew, Abbas.

Nasuh Pasha was an Ottoman statesman of Albanian origin. He was grand vizier of the Ottoman Empire from 5 August 1611 until 17 October 1614. He was from Gümülcine and was a damat to the Ottoman dynasty, as he married an Ottoman princess. He was executed by Ahmed I in 1614.

Sadik Achmet was a Turkish professor and politician. He founded the Party of Friendship, Equality and Peace.

John V Palaiologos or Palaeologus was Byzantine Emperor from 1341 to 1391.

Şerif Gören is a Turkish film director. Aside from important movies under his own signature, he is also the winner of the Palme d'Or award in Cannes Film Festival in 1982 for the film Yol, which he had directed on behalf of Yılmaz Güney, who at the time was serving a prison sentence for the murder of Yumurtalık judge Sefa Mutlu.

Anna-Maria Botsari is a Greek chess player holding the title of Woman Grandmaster (WGM).

John III Doukas Vatatzes, Latinized as Ducas Vatatzes, was Emperor of Nicaea from 1222 to 1254. He was succeeded by his son, known as Theodore II Laskaris.

Polygnotus was an ancient Greek painter from the middle of the 5th century BC.

Vassilis Vassilikos is a Greek writer and diplomat.

Nikephoros Bryennios was a Byzantine general, statesman and historian. He was born at Orestias in the theme of Macedonia.