List of Famous people born in City Municipality of Novo Mesto, Slovenia

Melania Trump is a Slovene-American former model and businesswoman. She was the first lady of the United States from 2017 to 2021, during the presidency of her husband, Donald Trump.

Miha Zarabec is a Slovenian handball player for THW Kiel and the Slovenian national team.

Edvard Ravnikar was a Slovenian architect.

Primož Kozmus is a Slovenian hammer thrower. His gold medals in the 2008 Summer Olympics in Beijing and the 2009 World Championships in Berlin made him the first ever Slovenian athlete to win both titles.

Domen Novak is a Slovenian cyclist, who currently rides for UCI WorldTeam Team Bahrain Victorious. He was named in the startlist for the 2017 Vuelta a España. In May 2018, he was named in the startlist for the 2018 Giro d'Italia.

Blaž Jarc is a Slovenian former professional cyclist, who competed professionally between 2007 and 2014.

Branko Filip is a former Slovenian cyclist he is current coach of the men's cycling team Torku Şekerspor of Turkey.

Martin Derganc is a Slovenian former professional road cyclist.

Igor Lukšič is a Slovenian political scientist, politician and was president of the Slovenian Social Democrats. Between November 2008 and February 2012, he served as Minister of Education in the center-left government of Borut Pahor.