List of Famous people born in Centre-Val de Loire, France

Adrien René Franchet was a French botanist, based at the Paris Muséum national d'Histoire naturelle.

Eugène Henri Brisson was a French statesman, Prime Minister of France for a period in 1885-1886 and again in 1898.

Achille Guenée was a French lawyer and entomologist.

François Coillard was a French missionary who worked for the Paris Evangelical Missionary Society in southern Africa.

Nicolas Chaperon was a French painter, draughtsman and engraver, a student in Paris of Simon Vouet whose style he adopted before he was further matured by his stay in Rome (1642–51) in the studio of Nicolas Poussin.

Jean de La Chapelle was a French writer and dramatist. He was born at Bourges, France, was elected to the Académie française in 1688, and died in Paris.

Auguste Moïse Daumain was a French racing cyclist who competed in the late 19th century and early 20th century. He participated in Cycling at the 1900 Summer Olympics in Paris and won the bronze medal in the men's 25 kilometre race. In the men's sprint, he finished third in the second heat and third in the fourth heat in the quarterfinals.

François Beaugendre was an early twentieth century French road racing cyclist who participated in the 1903 Tour de France and finished ninth overall. Beaugendre also rode the first four stages of the 1904 Tour de France, where he finished 7th, 11th, 3rd and 3rd, and did not start the fifth stage. Months after this Tour finished, many cyclists were disqualified, and Beaugendre's results were upgraded to 3rd, 6th, 2nd and 1st; Beaugendre was therefore declared winner of the fourth stage, and following the disqualifications he had been leader at the moment he left the race.

Léon Omer Beaugendre was a French cyclist who competed at the 1900 Summer Olympics in Paris and in the 1910 Tour de France. He won Paris–Tours in 1908. He was the brother of the cyclists François Beaugendre and Joseph Beaugendre.