List of Famous people born in Centre Macedonia Region, Greece

Kyriakos Papadopoulos is a Greek professional footballer who plays as a centre back for Prva HNL club Lokomotiva and the Greece national team.

Marinella is one of the most popular Greek singers whose career has spanned several decades. She has sung professionally since 1957. Since the beginning of her career, she has released 66 solo albums and has been featured on albums by other musicians.

Raphaël Salem (Greek: Ραφαέλ Σαλέμ; November 7, 1898 in Salonika, Ottoman Empire – June 20, 1963 in Paris, France), was a Greek mathematician after whom are named the Salem numbers and Salem–Spencer sets and whose widow founded the Salem Prize.

Anastasia Pazaiti-Karamanli (Greek: Αναστασία Παζαΐτη-Καραμανλή, is the wife of Kostas Karamanlis, former Prime Minister of Greece. She is a resident general surgeon.

Georgios Kostikos is a Greek former professional footballer.

Lazaros Voreadis. is a Greek basketball referee. Voreadis was born in Thessaloniki, Greece, and he speaks both Greek and English.

Vasilis Papageorgopoulos is a retired Greek sprinter, former mayor of Thessaloniki and convicted felon. He won two medals at the European Indoor Championships as well as the bronze medal in the 100 metres at the 1971 European Championships in Athletics.

Evanthia "Evina" Maltsi is a Greek former professional basketball guard. In 2007, she played for Connecticut Sun in the WNBA, appearing in 29 games, 26 in the regular season and 3 in the playoffs. A three time Euroleague All-Star (2007–2009), Maltsi has a long career in European club basketball, having played in Spain, France, Czech Republic, Poland and Turkey besides her native Greece and she has won numerous titles as a player of CJM Bourges, Ros Casares Valencia, USK Praha and Olympiacos.

Dimosthenis Tampakos is a Greek gymnast and Olympic gold medalist.

Ioannis Tamouridis is a Greek cyclist from Thessaloniki, Greece. He started cycling in 1995 and he competes in Road and Track races.