List of Famous people born in Castile and León, Spain

Álvaro Benito Villar is a Spanish retired footballer who played as a left midfielder, and is the vocalist/guitarist of Rock band Pignoise.

John of the Cross, venerated as Saint John of the Cross, was a Spanish Catholic priest, mystic, and a Carmelite friar of converso origin. He is a major figure of the Counter-Reformation in Spain, and he is one of the thirty-six Doctors of the Church.

Pablo Machín Díez is a Spanish retired footballer who played as a right back, and is a manager.

Adolfo Nicolás Pachón was a Spanish priest of the Roman Catholic Church. He was the thirtieth Superior General of the Society of Jesus from 2008 to 2016. Before being elected Superior General, he worked primarily in Japan; he taught at Sophia University in Tokyo for twenty years and then headed educational institutions in Manila from 1978 to 1984 and in Tokyo from 1991 to 1993. He led the Jesuits in Japan from 1993 to 1996 and, after four years of pastoral work in Tokyo, led the Jesuits in Asia from 2004 to 2008.

Francisco 'Paco' Llorente Gento is a Spanish retired footballer who played mostly as a right winger.

Carmelo Gómez Celada is a Spanish actor. He was born and worked in the village of Sahagún until he moved for his acting studies to Salamanca. He is the recipient of two Goya Awards, for best supporting actor in El método and best leading actor in Días contados.

Carlos Sastre Candil is a former Spanish professional road bicycle racer and winner of the 2008 Tour de France. He consistently achieved outstanding results in the Vuelta a España and in the Tour de France. Sastre established himself as a strong and stable climbing specialist, and after working to improve his individual time trial skills, he became a contender for the top GC spots in the Grand Tours. In total, Sastre finished in the top ten overall of fifteen Grand Tours during his career.

Ramón Ruiz Alonso (1901–1978) was a Spanish politician who was a right-wing activist during the Second Spanish Republic and typographer by trade. Married to actress Magdalena Penella, they had four daughters: Terele Pávez (1939-2017), Julia Ruiz Penella (1937-2017), Elisa Montés and Emma Penella (1931-2007). He led the arrest and subsequent murder of the famous Spanish poet Federico García Lorca, on the 19th of August 1936.

José Rojo Martín, known as Pacheta, is a Spanish former footballer who played as a midfielder, and is the current manager of SD Huesca.

Peter, called the Cruel or the Just, was the king of Castile and León from 1350 to 1369. Peter was the last ruler of the main branch of the House of Ivrea.