List of Famous people born in Castile and León, Spain

Alfonso of León, Lord of Molina was an infante (prince) of León and Castile, the son of King Alfonso IX of León and his second wife Queen Berengaria of Castile. He was the brother of King Ferdinand III of Castile and León, and father of Queen Maria of Molina, wife of King Sancho IV. He became Lord of Molina and Mesa after his first marriage to Mafalda González de Lara, the heiress of those lands.

Sergio Herrera Pirón is a Spanish footballer who plays for CA Osasuna as a goalkeeper.

Tomás Burgos Gallego is a Spanish politician who belongs to the People's Party (PP).

Sancho IV of Castile called the Brave, was the king of Castile, León and Galicia from 1284 to his death. He was the second son of Alfonso X and Yolanda, daughter of James I of Aragon.

Tomás Rodríguez Bolaños was a Spanish industrial technician and politician.

Segismundo Casado López was a Spanish Army officer in the Second Spanish Republic during the Spanish Civil War, commanding the Republican Spanish Army in 1939.

Carlos Garrote is a Spanish sprint canoeist.

María Teodora Adoracion ("Dori") Ruano Sanchón is a retired female track and road racing cyclist from Spain. She represented her native country at three Summer Olympics: in 1992, 2000, and 2004. Her biggest achievement was winning the world title in the women's points race at the 1998 UCI Track Cycling World Championships.

Alonso Fernández de Avellaneda is the pseudonym of a man who wrote a sequel to Cervantes' Don Quixote. The identity of Avellaneda has been the subject of many theories, but there is no consensus on who he was. It is not clear that Cervantes knew who Avellaneda was although he knew that it was a pseudonym and that the volume's publication information was false. One theory holds that Avellaneda's work was a collaboration by friends of Lope de Vega. Another theory is that it was by Gerónimo de Passamonte, the real-life inspiration for the character Ginés de Pasamonte of Part I.

Bernardo Luis de Velasco y Huidobro was a figure in the Spanish American wars of independence, the last Spanish governor of Paraguay and a commander of royalist military forces in the war. He was deposed by the congress celebrated in Asunción on 17 June 1811. He was born in Villadiego, Burgos, Spain.