List of Famous people born in Cape Girardeau, United States of America

Rush Hudson Limbaugh III is an American radio personality, conservative political commentator, author and former television show host. He is best known as the host of his radio show The Rush Limbaugh Show, which has been in national syndication on AM and FM radio stations since 1988.

David Scott Limbaugh is a conservative American political commentator and author who has also worked as a professor and as a lawyer. He is the younger brother of talk radio host Rush Limbaugh.

Andrew James Ellis, is an American former professional baseball catcher who is currently a Special Assistant to the General Manager in the front office of the San Diego Padres. Ellis played in Major League Baseball (MLB) for the Los Angeles Dodgers, Philadelphia Phillies, Miami Marlins, and the Padres, before retiring, following the 2018 season.

Mayer Jacob "Chic" Hecht was a Republican United States Senator from Nevada from 1983 to 1989 and U.S. Ambassador to the Bahamas from 1989 to 1993.

Linda Maxine Godwin Ph.D. is an American scientist and retired NASA astronaut. Godwin joined NASA in 1980 and became an astronaut in July 1986. She retired in 2010. During her career, Godwin completed four space flights and logged over 38 days in space. Godwin also served as the Assistant to the Director for Exploration, Flight Crew Operations Directorate at the Johnson Space Center. Since retiring from NASA, she accepted the position of Professor in the Department of Physics and Astronomy at the University of Missouri.

Richard Kinder is an American billionaire businessman. He is the co-founder and executive chairman of Kinder Morgan Inc., an energy and pipeline corporation.