List of Famous people born in Cali, Colombia

Lupe Fuentes is a Colombian house music producer, DJ, and former pornographic actress. She has been married to singer and actor Evan Seinfeld since 2011.

José Santacruz Londoño, also known as Chepe Santacruz, was a Colombian drug lord. Along with Gilberto Rodríguez Orejuela and Miguel Rodríguez Orejuela, Santacruz was a leader of the Cali Cartel.

Reinaldo Rueda Rivera is a Colombian football manager who is currently in charge of the Colombia national football team. In 2011, Rueda was naturalized as a Honduran citizen.

Duván Esteban Zapata Banguero is a Colombian professional footballer who plays as a striker for Italian club Atalanta and the Colombia national team.

Laura González Ospina, also known as Laura Barjum, is a Colombian actress, model and beauty pageant titleholder. She was Miss Colombia 2017 and later represented her country at the Miss Universe 2017 pageant, where she ended as 1st Runner-up.

Daniela Ramos Lalinde is a Colombian designer, model and beauty pageant titleholder who won Miss Mundo Colombia 2009 and represented Colombia at Miss World 2009 where she placed Top 7.

Juan Sebastián Cabal Valdés is a Colombian professional tennis player specialising in doubles. His current ranking in men's doubles is No. 2, and he has also reached world No. 184 in singles. He has won three Grand Slam doubles titles in his career, in 2017 he won the mixed doubles title at the Australian Open, partnering Abigail Spears of the US, and two years later he won his first men's doubles Grand Slam title, winning the 2019 Wimbledon title and 2019 US Open title alongside countryman and regular doubles partner, Robert Farah.

Gabriela Tafur Náder is a Colombian lawyer, model and beauty pageant titleholder who was crowned Miss Colombia 2018. She represented Colombia at Miss Universe 2019 and placed in the Top 5.

Johan Andrés Mojica Palacio is a Colombian professional footballer who plays for La Liga club Elche, on loan from Segunda División club Girona FC, and the Colombia national team. Mainly a left back, he can also play as a left winger.

Flavio Enrique "Kike" Santander Lora is a Colombian-American composer, record producer, arranger and entrepreneur. He is considered to be one of the principal Latino composers of the day, having worked with artists such as David Bisbal, Cristian Castro, Thalía, Chayanne, Diego Torres, Davi Wornel, Alejandro Fernández, Olga Tañón, Bacilos, José Luis Rodríguez «El Puma» and Gloria Estefan among others. Santander has composed more than 710 songs and has sold over 25 million albums worldwide. His work as songwriter and producer includes themes such as Let's Get Loud by Jennifer Lopez, Abriendo puertas by Gloria Estefan, Me Estoy Enamorando by Alejandro Fernández, Mi Vida Sin Tu Amor by Cristian Castro, and Premonición by David Bisbal, as well as many songs recorded by artists such as Thalía, Natalia Oreiro, Gisselle, Edith Márquez, Luis Miguel, Soledad Pastorutti and the Spanish song for Eurovision Song Contest 2004, amongst others.