List of Famous people born in Al Madinah Region, Saudi Arabia

Jamal Ahmad Khashoggi was a Saudi Arabian dissident, author, columnist for The Washington Post, and a general manager and editor-in-chief of Al-Arab News Channel who was assassinated at the Saudi consulate in Istanbul on 2 October 2018 by agents of the Saudi government. He also served as editor for the Saudi Arabian newspaper Al Watan, turning it into a platform for Saudi progressives.

Husayn ibn Ali ibn Abi Talib was a grandson of the Islamic prophet Muhammad and a son of Ali ibn Abi Talib and Muhammad's daughter Fatimah. He is an important figure in Islam as he was a member of the Household of Muhammad and the People of the Cloak, as well as the third Shia Imam.

Umar ibn Abd al-Aziz, commonly known as Umar II, was the eighth Umayyad caliph. He made various significant contributions and reforms to the society, and he has been described as "the most pious and devout" of the Umayyad rulers and was often called the first Mujaddid and fifth righteous caliph of Islam.

Abd al-Malik ibn Marwan ibn al-Hakam was the fifth Umayyad caliph, ruling from April 685 until his death. A member of the first generation of born Muslims, his early life in Medina was occupied with pious pursuits. He held administrative and military posts under Caliph Mu'awiya I, founder of the Umayyad Caliphate, and his own father, Caliph Marwan I. By the time of Abd al-Malik's accession, Umayyad authority had collapsed across the Caliphate as a result of the Second Muslim Civil War and had been reconstituted in Syria and Egypt during his father's reign.

Al-Hasan ibn Ali ibn Abi Talib, also spelled Hasan or Hassan, was the older son of Ali and Muhammad's daughter Fatimah, and was the older brother of Husain, as well as the fifth of Rashidun, or "Rightly Guided Caliphs". Muslims respect him as a grandson of the Islamic prophet Muhammad. Among Shia Muslims, Hasan is revered as the second Imam. Hasan was elected for the caliphate after his father's death, but abdicated after six or seven months to Muawiyah I, the founder of the Umayyad dynasty to end the First Fitna. After Hasan's abdication, the caliphate turned into kingship. Al-Hasan was known for donating to the poor, his kindness to the poor and bondsmen, and for his knowledge, tolerance and bravery. For the rest of his life, Hasan lived in Medina, until he died at the age of 45 and was buried in the Jannat al-Baqi cemetery in Medina. His wife, Ja'da bint al-Ash'at, is commonly accused of having poisoned him.

Malik ibn Anas, whose full name is Mālik bin Anas bin Mālik bin Abī ʿĀmir bin ʿAmr bin Al-Ḥārith bin Ghaymān bin Khuthayn bin ʿAmr bin Al-Ḥārith al-Aṣbaḥī al-Madanī, reverently known as al-Imām Mālik by Maliki Sunnis, was an Arab Muslim jurist, theologian, and hadith traditionist. Born in the city of Medina, Malik rose to become the premier scholar of prophetic traditions in his day, which he sought to apply to "the whole legal life" in order to create a systematic method of Muslim jurisprudence which would only further expand with the passage of time. Referred to as the "Imam of Medina" by his contemporaries, Malik's views in matters of jurisprudence were highly cherished both in his own life and afterwards, and he became the founder of one of the four schools of Sunni law, the Maliki, which became the normative rite for the Sunni practice of much of North Africa, Andalusia, a vast portion of Egypt, and some parts of Syria, Yemen, Sudan, Iraq, and Khorasan, and the prominent Sufi orders, including the Shadiliyya and the Tijaniyyah.

Zaynab bint Ali, also spelled Zainab, was the daughter of Ali ibn Abi Talib and Fatimah bint Muhammad. The Islamic Prophet Muhammad was her maternal grandfather, and thus she is a member of his Ahl al-Bayt. She is often revered not only for her characteristics and actions, but also for her membership in, and continuation of, the biological line of Muhammad. Like other members of her family, she is considered to be a figure of sacrifice, strength, and piety in both the Sunni and Shia sects of Islam.

Anas ibn Malik ibn Nadr al-Khazraji Al-Ansari (Arabic: أنس بن مالك الخزرجي الأنصاري‎ was a well-known sahabi of the Prophet of Islam.

Abd Allah ibn al-Zubayr ibn al-Awwam was the leader of a caliphate based in Mecca that rivaled the Umayyads from 683 until his death. The son of al-Zubayr ibn al-Awwam and Asma bint Abi Bakr, Ibn al-Zubayr belonged to the Quraysh, the leading tribe of the nascent Muslim community, and was the first child born to the Muhajirun, Islam's earliest converts. As a youth, he participated in the early Muslim conquests alongside his father in Syria and Egypt, and later played a role in the Muslim conquests of North Africa and northern Iran in 647 and 650, respectively. During the First Muslim Civil War, he fought on the side of his aunt A'isha against Caliph Ali. Though little is heard of Ibn al-Zubayr during the subsequent reign of the first Umayyad caliph Mu'awiya I, it was known that he opposed the latter's designation of his son, Yazid I, as his successor. Ibn al-Zubayr, along with much of the Quraysh and the Ansar, the leading Muslim groups of the Hejaz, opposed the caliphate becoming an inheritable institution of the Umayyads.

Abd al-Muttalib Shaybah ibn Hashim was the grandfather of Islamic prophet Muhammad.