List of Famous people born in Valle del Cauca Department, Colombia

Juana Acosta Restrepo is a Colombian-Spanish actress. She has appeared in more than forty films.

Óscar Andres Rivas Torres is a Colombian professional boxer who challenged for the vacant WBC interim heavyweight title in 2019. He has previously held the IBF International, WBC-NABF and WBO-NABO heavyweight titles. As an amateur he won a silver medal at the 2007 Pan American Games, and holds notable wins over Kubrat Pulev and Andy Ruiz Jr. As of August 2020, he is ranked as the world's tenth best active heavyweight by The Ring magazine.

Claudia Isabel Palacios Giraldo is a Colombian journalist and newscaster. She is best known as the weekend news anchor on CNN en Español, a position she held from 2004 through 2012. She is currently both a news anchor on CM& Television in Colombia and a journalist for the Colombian magazine El Pueblo.

Michael Egred Mejía artistically known as Mike Bahía, is a Colombian singer and enterprise administrator. He is best known for his songs "Estar Contigo", "Buscándote", "La Muñeca", and his most recent collaboration "Amantes", with Greeicy Rendón.

Óscar Eduardo Córdoba Arce is a retired Colombian footballer who played as a goalkeeper. He has played more than 70 games for the Colombia national team. He is also the only person to never concede a goal in a Copa América edition, having done so in 2001.

Juan Felipe Samper better known as "SAMPER" is a musician, songwriter, Colombian pop rock singer winner of 2 Premios Shock, 1 Premios Nuestra Tierra and Latin Grammy nominee.

Yimmi Javier Chará Zamora is a Colombian footballer who plays as a right winger for MLS club Portland Timbers and the Colombia national team.

Gustavo Álvarez Gardeazábal is a Colombian writer, and politician. He attended the University of Valle and was the runner-up for a Premio Nadal in 1971 for Dabeiba. He was awarded a Guggenheim Fellowship in 1984. and was Governor of Valle del Cauca Department from 1998–1999. He also wrote the highly rated telenovela El Bazar de los Idiotas. He is one of the few atheists to hold public office in Colombia.

Daniela Ramos Lalinde is a Colombian designer, model and beauty pageant titleholder who won Miss Mundo Colombia 2009 and represented Colombia at Miss World 2009 where she placed Top 7.

Fanny Lucía Martínez Buenaventura, better known professionally as Fanny Lu, is a Colombian singer, songwriter and actress from Santiago de Cali, Colombia. She studied at the University of the Andes and received a degree in industrial engineering. She is the mother of two children, Mateo and Valentina.