List of Famous people born in Tarapacá Region, Chile

Edson Raúl Puch Cortez is a Chilean footballer who plays as a forward for Primera Division club Universidad Católica and the Chile national team.

Juan Zanelli (1906–1944) was a Chilean racecar driver. He was born in Iquique, Chile in 1906. He raced in Grand Prix motor racing and hillclimbs from 1929 to 1936. In a Bugatti he won the 1929 and 1930 Bugatti GP at Le Mans, finished 8th in Alessandria in 1929 and 2nd in 1930, 2nd at the 1929 Marne GP and 3rd at the 1930 French GP at Pau. He won the 1933 Penya Rhin Grand Prix in Barcelona, Spain in an Alfa Romeo.

Brayan Josué Cortés Fernández is a Chilean footballer that currently plays for Primera División club Colo-Colo as goalkeeper.

Fulvio Fabrizio Rossi Ciocca is a Chilean politician and physician.

Marco Antonio Órdenes Fernández is a native of Chile and a former prelate of the Catholic Church. He was Bishop of Iquique from 2006 to 2012. When appointed at the age of 42, he was the youngest bishop in the history of Chile. Accusations that he had sexually abused minors forced his resignation in 2012. Civil procedures concluded when prosecutors could not establish a case against him, but church proceedings ended with his removal from the clerical state in 2018.

Hugo Humberto Gutiérrez Gálvez is a Chilean politician who was elected as a member of the Chilean Constitutional Convention.