List of Famous people born in South Holland, Kingdom of the Netherlands

Regnier de Graaf, original Dutch spelling Reinier de Graaf, or Latinized Reijnerus de Graeff was a Dutch physician and anatomist who made key discoveries in reproductive biology. His first name is often spelled Reinier or Reynier.

Remco Campert is a Dutch author, poet and columnist.

Constantijn Huygens Jr., Lord of Zuilichem was a Dutch statesman and poet, mostly known for his work on scientific instruments. But, he was also a chronicler of his times, revealing the importance of gossip. Besides he was an amateur draughtsman of landscapes.

Prince Maurice of the Netherlands, Prince of Orange-Nassau, was the second son of King William III of the Netherlands and his first spouse, Sophie of Württemberg.

Dirk Jan Struik was a Dutch-born American mathematician, historian of mathematics and Marxian theoretician who spent most of his life in the U.S.

Abraham Bloemaert was a Dutch painter and printmaker in etching and engraving. He was initially working in the style of the "Haarlem Mannerists", but in the 16th century altered his style in line with the new Baroque style that was then developing. He mostly painted history subjects and some landscapes. He was an important teacher, who trained most of the Utrecht Caravaggisti, at least for a period.

Charley Toorop was a Dutch painter and lithographer. Her full name was Annie Caroline Pontifex Fernhout-Toorop.

Count Claus-Casimir of Orange-Nassau, Jonkheer van Amsberg, is the second child of Prince Constantijn and Princess Laurentien of the Netherlands and their only son. He is a member of the Dutch Royal Family and is sixth in the line of succession to the Dutch throne.