List of Famous people born in South Carolina, United States of America

Joseph Leonard Goldstein ForMemRS is an American biochemist. He received the Nobel Prize in Physiology or Medicine in 1985, along with fellow University of Texas Southwestern researcher, Michael Brown, for their studies regarding cholesterol. They discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develop hypercholesterolemia and become at risk for cholesterol related diseases, notably coronary heart disease. Their studies led to the development of statin drugs.

Charles Frank Bolden Jr. is a former NASA administrator, a retired United States Marine Corps Major General, and a former astronaut who flew on four Space Shuttle missions.

Nate Diana Stevenson or simply ND Stevenson is an American cartoonist and animation producer. He is the creator, showrunner, and executive producer of the animated television series She-Ra and the Princesses of Power which ran from 2018 to 2020. He is also known for the fantasy webcomic Nimona, his work on the comics series Lumberjanes, and his autobiographical collection, The Fire Never Goes Out.

Andy Duncan is an American science fiction and fantasy writer whose work frequently deals with Southern U.S. themes.

Lauren Michelle Hill is an American model and actress. She first appeared on the cover of Playboy on the October 2000 issue. She was chosen as Playboy Playmate of the Month in February 2001 and won the Playboy playmates edition of the game show Fear Factor. Hill then returned for Fear Factor 's Tournament of Champions for season 2, but was eliminated in the second round. She was a cheerleader at the University of South Carolina while studying journalism. While modeling and acting, she is known as Lauren James. She was first spotted by a Playboy scout at a swimsuit competition in St. Croix.

Catherine Grace "Cady" Coleman is an American chemist, a former United States Air Force colonel, and a retired NASA astronaut. She is a veteran of two Space Shuttle missions, and departed the International Space Station on 23 May 2011, as a crew member of Expedition 27 after logging 159 days in space.

Julianne Morris is an American actress.

James Wesley "Bubber" Miley was an American early jazz trumpet and cornet player, specializing in the use of the plunger mute.

Anita Zucker is an American billionaire businesswoman and philanthropist. She was the chair at the Hudson's Bay Company. Taking over after her husband's death, she is now the chairperson and chief executive officer (CEO) of The Intertech Group. She is the wealthiest person to reside in the state of South Carolina.

William "Bo" Hopkins is an American actor. He is perhaps best known for playing important supporting roles in a number of major studio films between 1969 and 1979, and appeared in many other television shows and tv movies.