List of Famous people born in Santiago Metropolitan Region, Chile

Ivo Alexie Basay Hatibović is a retired football striker from Chile, who played professional football for seventeen years. Apart from being a regular choice for the Chile national football team in the late 1980s and early 1990s, he played club football for Magallanes, Curicó Unido, Everton, Colo Colo, Stade Reims, Necaxa and Boca Juniors.

Juan Emilio Cheyre Espinoza is a retired Chilean Army General. He was Commander-in-Chief of the Chilean Army from 2002 to 2006. As Commander-in-Chief he attempted to distance the Army from former dictator General Augusto Pinochet, and condemned the human rights abuses of Pinochet's dictatorship.

Juan Carlos Darío Gaete Contreras, known as Juan Carlos Gaete, is a Chilean footballer who plays as a winger for Chilean club Colo-Colo.

Denisse Alejandra Malebrán Soto, known as Denisse Malebrán, is a Chilean singer, songwriter and vocalist. She is member of the synthpop band, Saiko. She was a contestant on Dancing with the Stars.

María José Prieto Larraín is a Chilean film and television actress.

Paulina Nin de Cardona Muñoz is a Chilean primary school teacher and television presenter. She has worked in TVN's news program 60 Minutos, and conducted Canal 13's morning show La Mañana, in 1999.

Juan José Gurruchaga Vergara is a Chilean television actor.

Andrés Palacios is a Chilean-Mexican actor.

Bárbara Ruiz-Tagle Correa is a Chilean actress of theater and television.

Rodrigo Osvaldo Valdés Pulido is a Chilean economist and politician who served as minister of finance from May 11, 2015 to August 31, 2017 under president Michelle Bachelet.