List of Famous people born in Samtskhe–Javakheti, Georgia

Nodar Kumaritashvili was a Georgian luge athlete who suffered a fatal crash during a training run for the 2010 Winter Olympics competition in Whistler, British Columbia, Canada, on the day of the opening ceremony. He became the fourth athlete to die during preparations for a Winter Olympics, and the seventh athlete to die in either a Summer or Winter Olympic Games.

Gregorio Pietro XV Agagianian was an Armenian Cardinal of the Catholic Church. He was the head of the Armenian Catholic Church from 1937 to 1962 and supervised the Catholic Church's missionary work for more than a decade, until his retirement in 1970. He was considered papabile on two occasions.

Grand Duke Sergei Mikhailovich of Russia was the fifth son and sixth child of Grand Duke Michael Nikolaievich of Russia and a first cousin of Alexander III of Russia.

Vagharshak Varrnazi Harutiunyan or Vagharshak Varnazovich Arutyunyan was the Defence Minister of Armenia from 11 June 1999 until 20 May 2000 and again since November 20, 2020.

Hovhannes Kajaznuni, or Hovhannes Katchaznouni, was the first Prime Minister of the First Republic of Armenia from June 6, 1918 to August 7, 1919. He was a member of the Armenian Revolutionary Federation.

Hennadiy Petrovich Vorobiov was a Ukrainian Colonel general and Commander of the Ground Forces of Ukraine from November 2009 to January 2014.

Stepanos Sargsi Malkhasyants was an Armenian academician, philologist, linguist, and lexicographer. As an expert in classical Armenian literature, Malkhasyants wrote the critical editions and translated the works of many classical Armenian historians into modern Armenian and contributed 70 years of his life to the advancement of the study of the Armenian language.