List of Famous people born in Pennsylvania, United States of America

Craig Douglas McCracken is an American animator and writer. He created the Cartoon Network animated television series The Powerpuff Girls and Foster's Home for Imaginary Friends, as well as Wander Over Yonder for the Disney Channel. McCracken has previously served as an art director and storyboard artist for 2 Stupid Dogs and Dexter's Laboratory respectively. He has been married to fellow animator Lauren Faust since 2004. He created and executive produced Kid Cosmic, an animated series for Netflix, which premiered in February 2021.

Bertram Myron Gross was an American social scientist, Federal bureaucrat and Professor of Political Science at Hunter College (CUNY). He is known from his book Friendly Fascism: The New Face of Power in America from 1980, and as primary author of the Humphrey–Hawkins Full Employment Act.

Ignatius "Iggie" Wolfington was an American actor. He was the youngest member of the prominent Wolfington family of Philadelphia, operators of a carriage business early in the 20th century and brother of the founder of Wolfington Body Company in Exton, Pennsylvania. He married Lynn Wood, an actress, in 1972.

Albert Ellis was an American psychologist and psychotherapist who founded Rational Emotive Behavior Therapy (REBT). He held MA and PhD degrees in clinical psychology from Columbia University, and was certified by the American Board of Professional Psychology (ABPP). He also founded, and was the President of, the New York City-based Albert Ellis Institute. He is generally considered to be one of the originators of the cognitive revolutionary paradigm shift in psychotherapy and an early proponent and developer of cognitive-behavioral therapies.

William Daniel Phillips is an American physicist. He shared the Nobel Prize in Physics, in 1997, with Steven Chu and Claude Cohen-Tannoudji.

Harold F. Kress was an American film editor with more than fifty feature film credits; he also directed several feature films in the early 1950s. He won the Academy Award for Best Film Editing for How the West Was Won (1962) and again for The Towering Inferno (1974), and was nominated for four additional films; he is among the film editors most recognized by the Academy of Motion Picture Arts & Sciences. He also worked publicly to increase the recognition of editing as a component of Hollywood filmmaking.

Henry Bean is an American screenwriter, film director, film producer, novelist, and actor.

Hardie Hunter Albright was an American actor.

Arthur Blakey was an American jazz drummer and bandleader. He was briefly known as Abdullah Ibn Buhaina after he converted to Islam for a short time in the late 1940s.

John Michael Bishop is an American immunologist and microbiologist who shared the 1989 Nobel Prize in Physiology or Medicine with Harold E. Varmus and was co-winner of 1984 Alfred P. Sloan Prize. He serves as an active faculty member at the University of California, San Francisco (UCSF), where he also served as chancellor from 1998 to 2009.