List of Famous people born in Missouri, United States of America

Michael Harold Coffman is an American politician, businessman, and veteran of the U.S. Army and U.S. Marine Corps serving as Mayor of Aurora, Colorado since 2019. A Republican, Coffman served as the U.S. Representative for Colorado's 6th congressional district for five terms, as well as Secretary of State of Colorado and Colorado State Treasurer.

Alice Margaret Ghostley was an American actress and singer. She was best known for her roles as Esmeralda on Bewitched, as Cousin Alice (1970–71) on Mayberry R.F.D., and as Bernice Clifton (1986–93) on Designing Women, for which she received an Emmy nomination for Best Supporting Actress in a Comedy Series in 1992. She was a regular on Nichols (1971–72) and The Julie Andrews Hour (1972–73).

Carl E. Guthrie was an American cinematographer.

Brent Sexton is an American actor best known for his roles in the television series Bosch, The Killing, Life, and Deadwood. He has guest starred in several other television series, such as Justified, That's Life, Birds of Prey, Law & Order: Special Victims Unit, and Judging Amy. He has also appeared in several motion pictures, such as In the Valley of Elah, Flightplan, Radio, and A.I. Artificial Intelligence.

Carl Sanford Joslyn "Sandy" Petersen is an American game designer.

Jeremiah Wilson "Jay" Nixon is an American politician and lawyer who served as the 55th Governor of Missouri from 2009 to 2017. A member of the Democratic Party, he was first elected to the governorship in 2008 and reelected in 2012. Prior to his tenure as Missouri Governor, he served as the 40th Missouri Attorney General from 1993 to 2009. After leaving public office he joined the Dowd Bennett law firm in St. Louis. As of 2021, he is the last Democrat to serve as the Governor of Missouri.

John Joseph Leibrecht is an American prelate of the Roman Catholic Church. He served as Bishop of Springfield-Cape Girardeau from 1984 to 2008.

Billy Ray Sims is a former American college and professional football player who was a running back in the National Football League (NFL) for five seasons during the 1980s. Sims played college football for the University of Oklahoma, where he was a two-time consensus All-American, and won the Heisman Trophy in 1978. He was the first overall pick in the 1980 NFL Draft, and played professionally for the NFL's Detroit Lions. Sims was the last Oklahoma player taken Number 1 overall in the NFL Draft until quarterback Sam Bradford was taken first in the 2010 NFL Draft. He was given the nickname "Kung Fu Billy Sims" by ESPN's Chris Berman, after a game where the Detroit Lions played the Houston Oilers. In the NFL Films highlight, rather than be tackled during a rushing attempt, Sims ran at, jumped, and, while fully airborne, kicked Oilers Cornerback Steve Brown in the head.

Bill Chott is an American actor and comedian. He is best known for his role as Mr. Laritate on the Disney Channel Original Series Wizards of Waverly Place.

Bessie Potter Vonnoh was an American sculptor best known for her small bronzes, mostly of domestic scenes, and for her garden fountains. Her stated artistic objective, as she told an interviewer in 1925, was to “look for beauty in the every-day world, to catch the joy and swing of modern American life.”