List of Famous people born in Missouri, United States of America

Steven Jay Hatfill is an American physician, pathologist and biological weapons expert. He became the subject of extensive media coverage beginning in mid-2002, when he was a suspect in the 2001 anthrax attacks. His home was repeatedly raided by the FBI, his phone was tapped, and he was extensively surveilled for more than two years; he was also fired from his job at Science Applications International Corporation (SAIC). At a news conference in August 2002, Hatfill denied that he had anything to do with the anthrax letters and said "irresponsible news media coverage based on government leaks" had "destroyed his reputation". He filed a lawsuit in 2003, accusing the FBI agents and Justice Department officials who led the criminal investigation of leaking information about him to the press in violation of the federal Privacy Act.

Cori Anika Bush is an American politician, registered nurse, pastor, and activist serving as the U.S. Representative for Missouri's 1st congressional district. The district includes all of the city of St. Louis and most of northern St. Louis County.

Cedric Antonio Kyles, better known by his stage name Cedric the Entertainer, is an American actor, stand-up comedian, and game show host. He hosted BET's ComicView during the 1993–1994 season and Def Comedy Jam in 1995. He is best known for co-starring with Steve Harvey on The WB sitcom The Steve Harvey Show, as one of The Original Kings of Comedy, and for starring as Eddie Walker in Barbershop. He also stars on the CBS show The Neighborhood. He hosted the 12th season of the daytime version of Who Wants to Be a Millionaire in 2013–14 and starred in the TV Land original series The Soul Man, which aired from 2012 to 2016. He has also done voice work for Ice Age, the Madagascar film series, Charlotte's Web, Planes and Planes: Fire & Rescue. In 2019, he received a star on the Hollywood Walk of Fame.

Rebekah West Harkness also known as Betty Harkness, was an American composer, sculptor, dance patron, and philanthropist who founded the Harkness Ballet. In 1947, she married William Hale "Bill" Harkness, an attorney and heir to the Standard Oil fortune of William L. Harkness, which made her one of the wealthiest women in America. In addition to her marriage, Harkness also became well known for her personal eccentricities, as well as her contributions to the arts.

George Washington Carver was an American agricultural scientist and inventor who promoted alternative crops to cotton and methods to prevent soil depletion. He was the most prominent black scientist of the early 20th century.

Denis Patrick Seamus O'Hare is an American actor, singer, and author noted for his award-winning performances in the plays Take Me Out and Sweet Charity, as well as portraying vampire king Russell Edgington on HBO's fantasy series True Blood. He is also known for his supporting roles in such films as Charlie Wilson's War, Milk, Changeling, and Dallas Buyers Club. In 2011, he starred as Larry Harvey in the first season of the FX anthology series American Horror Story, for which he was nominated for a Primetime Emmy Award for Outstanding Supporting Actor in a Miniseries or a Movie in 2012. He returned to the show in 2013, playing Spalding in American Horror Story: Coven and once more as Stanley in American Horror Story: Freak Show, the latter for which he earned a second Primetime Emmy Award nomination. For his performance in American Horror Story: Hotel as Liz Taylor, O'Hare received critical acclaim.

Clay Shirky is an American writer, consultant and teacher on the social and economic effects of Internet technologies and journalism.

Roy Dean Blunt is an American politician serving as the senior United States senator for Missouri, serving since 2011. A member of the Republican Party, he previously served as a member of the United States House of Representatives and as Missouri Secretary of State.

Leland Tyler Wayne, professionally known as Metro Boomin, is an American record producer, record executive, songwriter, and DJ managed by SAL&CO. Raised in St. Louis, Wayne began a production career while in high school and became known for his successful recordings with Atlanta hip hop and trap artists such as Future, 21 Savage, Gucci Mane, and Migos in the mid-2010s. In 2017, Forbes called him "easily one of the most in-demand hitmakers in the world", while Stereogum described him as "one of the most original, vivid, important voices in rap right now".

William Payne Stewart was an American professional golfer who won eleven PGA Tour events, including three major championships in his career, the last of which occurred a few months before he died in an airplane accident at the age of 42.