List of Famous people born in Maule Region, Chile

Mario Luis Kreutzberger Blumenfeld, better known by his stage name as Don Francisco, is a Chilean television host, and a popular personality on the Univision network reaching Spanish-speaking viewers in the United States. In 2016, he signed into Telemundo. He is best known for hosting the former variety shows Sábado Gigante and Don Francisco Presenta.

Cristian Antonio Montecinos González a retired Chilean football player who played for several teams in Chile, Colombia, Mexico, United Arab Emirates and Qatar. He also played as for the Chilean national team.

Gonzalo Fernando Blumel Mac-Iver is a Chilean politician, civil environmental engineer and economist who served as Minister of the Interior and Public Security of Chile during Sebastián Piñera second government (2018–2022).

Raúl Florcita Alarcón Rojas, popularly known as Florcita Motuda, is a Chilean musician and politician. He currently serves as National Deputy in the Chamber of Deputies since March 2018, representing district 17. He was one of the most historical member of the Humanist Party. He is well-known for his flamboyant style for clothing and musical work, even when serving as Deputy.

Ángelo Nicolás Sagal Tapia is a Chilean footballer who plays as a forward for Turkish Süper Lig club Denizlispor.

Matías Duarte is a Chilean computer interface designer and Google's Vice President of Design. Prior to his current role, he was the Director of Android User Experience. Android 3.0 "Honeycomb" was the first release with major elements of his design influence.

Catalina Parot Donoso is a Chilean lawyer, entrepreneur and politician currently serving as president of the National Television Council.

Guillermo Arturo Ceroni Fuentes is a Chilean politician who served as a member of the Chamber of Deputies, representing District 40 of the Maule Region. He served as Provisional President of the Chamber of Deputies following the death of Juan Bustos.

Raúl Eduardo Iturriaga Neumann is a Chilean Army general and a former deputy director of the DINA, the Chilean secret police under the Augusto Pinochet military dictatorship. He was in charge of a secret detention center known as La Venda Sexy and La Discothèque—because of the sexual abuse inflicted on blindfolded prisoners as loud music masked their screams. An aide to General Manuel Contreras, head of the DINA, he was in charge of several assassinations carried out as part of Operation Condor. He has been condemned in absentia in Italy for the failed murder of Christian-Democrat Bernardo Leighton, and is wanted both in Spain and in Argentina. In the latter country, he is accused of the assassination of General Carlos Prats.

Iván Andrés Morales Bravo is a Chilean footballer who currently plays for the Primera División de Chile team Colo-Colo as forward.