List of Famous people born in Marche, Italy

Giulia della Rovere was an Italian noblewoman. A portrait of her by Titian survives in the Palazzo Pitti in Florence.

Pope Sixtus V, born Felice Piergentile, was the bishop of Rome from 24 April 1585 to his death. As a youth, he joined the Franciscan order, where he displayed talents as a scholar and preacher, and enjoyed the patronage of Pius V, who made him a cardinal. As a cardinal, he was known as Cardinal Montalto.

Franco Cassano was an Italian sociologist and politician. He was full professor of Sociology and Sociology of Cultural and Communicative Processes at the University of Bari Aldo Moro, alongside his academic activity that of essayist and columnist. Among his best-known works Il pensiero meridiano (1996) and L'umiltà del male (2011). In the 2013 political elections he was elected deputy of the XVII legislature of the Italian Republic in the XXI Puglia constituency for the Democratic Party.

Laura Martinozzi was a Duchess consort of Modena by marriage to Alfonso IV d'Este, Duke of Modena. She served as regent of Modena during the minority of her son Francesco from 1662 until 1674.

Francesco Maria II della Rovere was the last Duke of Urbino.

Federico II Paolo Novello da Montefeltro was Count of Urbino from 1364 until his death. He was the son of Nolfo da Montefeltro. He had four sons, of which Antonio returned to become Count of Urbino in 1364.

Jacob de Marchia, commonly known in English as St. James of the Marches, O.F.M., was an Italian Friar Minor, preacher and writer. He was a Papal legate and Inquisitor.

Giulio della Rovere, also known as Giulio Feltrio della Rovere was an Italian Cardinal of the Catholic Church and a member of the della Rovere family.

Elisa Di Francisca is an Italian foil fencer, Olympic champion in 2012, World champion in 2010 and three-time European champion. She won the 2010–11 World Cup series and has seven World Cup victories to her name. With the Italian team, she was Olympic champion in 2012, five-time World champion and seven-time European champion.