List of Famous people born in Managua Department, Nicaragua

Román Alberto González Luna, best known by his nickname "Chocolatito", is a Nicaraguan professional boxer. He is the first boxer from Nicaragua to win world titles in four weight classes, having surpassed his mentor, idol, and former three-weight world champion, the late Alexis Argüello. González is also the first boxer in history to win world titles in all four of the lowest weight classes: minimumweight, light flyweight, flyweight, and super flyweight.

Rosario María Murillo Zambrana is the vice president and first lady of Nicaragua. She is married to the current president Daniel Ortega. She was also first lady when, in 1985, her husband became president six years after the Sandinista National Liberation Front (FSLN) overthrew the Somoza dynasty. Murillo has served as the Nicaraguan government's lead spokesperson, government minister, head of the Sandinista Association of Cultural Workers, and Communications Coordinator of the Council on Communication and Citizenry. She was sworn in as vice president of Nicaragua on 10 January 2017.

Bianca Jagger is a Nicaraguan social and human rights advocate and a former actress. Jagger currently serves as a Council of Europe goodwill ambassador, founder and chair of the Bianca Jagger Human Rights Foundation, member of the Executive Director's Leadership Council of Amnesty International USA, and a trustee of the Amazon Charitable Trust.

Ricardo Antonio Mayorga Perez is a Nicaraguan ex professional boxing and former mixed martial artist. In boxing he is a former two-weight world champion, having held the unified WBA (Super), WBC, Ring magazine, and lineal welterweight titles in 2003, and the WBC super welterweight title from 2005 to 2006. Mayorga first became well known to boxing fans upon being featured on the cover of The Ring's December 2003 issue, entitled "The craziest man in the sport: Mayorga lights up boxing." He has since maintained this infamous reputation with his relentless trash-talk in the build-up to most of his fights, as well as his smoking and drinking habits outside the ring.

Claudia Maria Poll Ahrens is a Costa Rican swimmer who competes in the 200 m to 800 m freestyle events. She is Costa Rica's only Olympic gold-medalist, having won the country's first Olympic gold medals at the 1996 Olympics in the 200 meter freestyle. She is a multiple national record holder in the freestyle events.

Sylvia Poll Ahrens is an Olympic and National Record holding swimmer from Costa Rica. At the 1988 Olympics, she won Costa Rica's first Olympic medal, when she garnered the silver in the women's 200 free. As of 2009, she and her younger sister Claudia are Costa Rica's only Olympic medalists. Sylvia also swam for Costa Rica at the 1992 Summer Olympics.

Xiomara Blandino is a Nicaraguan architecture student who held the title of Miss Nicaragua 2007.She participated in the Miss Universe 2007 contest representing Nicaragua and made it to the semifinals. She placed 10th overall where Miss Japan Riyo Mori went on to win the title.

Rolando José Álvarez Lagos is a Nicaraguan prelate of the Catholic Church. He has served as the Bishop of Matagalpa since 2011 and apostolic administrator of Estelí since 2021.