List of Famous people born in Maldonado Department, Uruguay

Nahitan Michel Nández Acosta is an Uruguayan professional footballer who plays as a midfielder for Italian club Cagliari Calcio and the Uruguay national team.

Gregorio Elso Pérez Perdigón is a retired Uruguayan footballer. In December of 2019, he was announced as the new manager of Peruvian side Universitario de Deportes. He is widely reputed in his country due for his respectful approach toward the game and general sportsmanship. He is known as "Don Gregorio".

Martín Nicolás Campaña Delgado is a Uruguayan footballer who plays as a goalkeeper for Saudi Professional League club Al-Batin and the Uruguay national team.

Matías Britos Cardoso, commonly known as Matías Britos, is a Uruguayan footballer who plays as a striker for Peñarol. He also holds Mexican citizenship.

Gabriel Neves Perdomo is a Uruguayan professional footballer who plays as a midfielder for Nacional and the Uruguay national team.

Jorge Hernán Menosse Acosta is a Uruguayan footballer who plays as a central defender for Deportivo Cali.

Arturo Eduardo Fajardo Bustamante is a Uruguayan Roman Catholic cleric.