List of Famous people born in Makkah Region, Saudi Arabia

Ahmed Al Mousa is a Saudi Arabian footballer. He started his career with Al Ittihad before joining Al Wahda. He led Al Wahda to third place in the regular season before beating defending champions Al Shabab in the quarter-finals of the league championship play-off.

Essa Mohhmad Humod Al Mehyani Al Hothaili is a Saudi Arabian football player. He currently plays as a striker.

Abu al-As ibn al-Rabi' was a son-in-law and companion of the Islamic prophet Muhammad. His original name was said to have been Hushaym or Yasser.

Hadi Soua'an Al-Somaily is a Saudi Arabian athlete. He won the first Saudi silver medal in the Olympics in the 400 metres hurdles, clocking a personal best time of 47.53 seconds in 2000 in Sydney. US sprinter Angelo Taylor won the race and the gold medal in 47.50 seconds.

Professor 'Abdulfattah bin Suleiman Al Mashat is the Rector of the newly established Jeddah University, Saudi Arabia since June 23, 2016. He was previously at King Abdulaziz University, holding the positions of Dean of Admission and Registration, director of the Center for Information Technology from 2004–2006, Dean of the Faculty of Computing and Information Technology from 2012 to 2016, both at King Abdulaziz University. ad then Vice Rector for Development.

Salman Al-Moasher is a Saudi Arabian footballer who plays as a winger for Pro League club Al-Ahli and the Saudi Arabian national team.

Mujahid ibn Jabr was a Tabi‘in and one of the major early Islamic scholars.

Omar Al-Ghamdi was a Saudi Arabian football player who played as defensive midfielder and played at left back.

Safiyya bint Abd al-Muttalib was a companion and aunt of the Islamic prophet Muhammad.

Fouad Ahmad Alfarhan is a popular Saudi Arabian blogger and political commentator noted for his advocacy of political reforms on his blog. Farhan is unusual among Saudi Arabian bloggers because he uses his real name rather than blogging under a pseudonym. Farhan had stopped blogging for a period after being told by government officials to "tone down" his commentary. He resumed posting in July 2007. On Tuesday, December 10, 2007 Farhan was arrested in Jeddah. The arrest was reported by other Arab bloggers, and Saudi authorities confirmed he was being held for "interrogation." No official charges were relayed. He was held in solitary confinement without charges. He was released from prison on April 26, 2008.