List of Famous people born in Makkah Region, Saudi Arabia

Waleed Sami Abulkhair is a Saudi Arabian lawyer and human rights activist, and the head of the Monitor of Human Rights in Saudi Arabia (MHRSA) organization. He is the first activist to be prosecuted by the Terrorism Law. He was arrested on April 15, 2014, and was sent to al-Ha'ir Prison while awaiting prosecution. On July 6, 2014, Abulkhair was sentenced to 15 years in prison by the Specialized Criminal Court, and a travel ban for another 15 years, in addition to a fine of 200,000 riyals (US$53,333). On January 12, 2015, the case returned to the Court of Appeals, after which the judge requested increasing the previous sentence, because Abulkhair refused to apologize. Thus, the judgment was tightened to 15-year executed. In response, Abulkhair prayed for God's victory and refused to recognize the legitimacy of the Specialized Criminal Court. Abulkhair is incarcerated in the Dhahban Central Prison in Jeddah, Saudi Arabia, a facility used to hold high-profile political prisoners, as well as members of Al Qaeda and the Islamic State.

Adel bin Muhammad Fakeih is a Saudi Arabian engineer and the former mayor of Jeddah. He was the minister of labor from 18 August 2010 to April 2015. Between 21 April 2014 and 8 December 2014 he also served as the minister of health. He was the minister of economy and planning between 2015 and 2017.

Heba Elsewedy is an Egyptian humanitarian who is a prominent figure in the public life of Egypt. She is the Founder of Ahl Masr Foundation, a non-governmental organization that specializes in caring physically and psychologically for burn victims. She was recognized for her many initiatives and saving thousands. Some people refer to her as "Mother Teresa" of Egypt and “Mama Heba.”

Hashim ibn Utba ibn Abi Waqqas was a Muslim army commander. He was Sa'd ibn Abi Waqqas nephew through his father, and was a Companions of the Prophet Muhammad. Hāshim participated in the Ridda wars against the rebellious Arabic tribes following the death of Mohammad in order to return them to Islam. He fought the Byzantines in Battle of Yarmouk under the command of Khalid ibn al-Walid. He played a vital role in the Battle of al-Qādisiyyah that led to the conquest of Al-Mada'in by Muslims. He died in Battle of Siffin fighting on the side of Ali.

Walid Fitaihi is a Saudi-American physician and also a motivational speaker on Saudi television. In November 2017, a decade after returning from study and work in the United States, Fitaihi was arrested by Saudi authorities and taken to the Ritz Carlton hotel as part of the 2017–19 Saudi Arabian purge, together with many prominent prisoners. He was later moved to al-Hair prison, south of the capital.

Khalid Massad Al-Muwalid is a retired Saudi Arabian footballer. He played most of his career for Al Ahli and Al Ittihad.

Iyad bin Amin Madani is a Saudi politician who served in different cabinet posts. He was the secretary general of the Organisation of Islamic Cooperation from 2014 to November 2016. He was the first Saudi official to hold that position.

Abdulaziz bin Talal bin Abdulaziz Al Saud is a Saudi Arabian prince and businessman.

Bakr bin Mohammed bin 'Awad bin Laden is the former chairman of the Jeddah-based Saudi Binladin Group and the former largest shareholder in the Group, with a 23.58% holding, and, according to some, was the "true ruler of Jeddah". He is the son of the family's patriarch − Mohammed bin Awad bin Laden − and a half-brother of Osama bin Laden.

ʿUtbah ibn Rabīʿah (c.563-624), also known as Abu al-Walid was one of the prominent pagan leaders of the Quraysh during the era of Muhammad. He is the father of Abu Hudhayfa ibn 'Utba, Walid ibn Utbah, Hind bint Utbah and father-in-law of Abu Sufyan ibn Harb. Utbah was killed by Hamza ibn Abdul-Muttalib in the Battle of Badr.