List of Famous people born in Khmelnytskyi Oblast, Ukraine

Valentina Ivanovna Matviyenko is a Russian politician serving as the Senator from Saint Petersburg and Chairwoman of the Federation Council since 2011. Previously she was Governor of Saint Petersburg from 2003 to 2011.

Lesia Ivanivna Nikitiuk — Ukrainian TV presenter.

Oksana Shachko was a Ukrainian artist and activist. Along with Anna Hutsol and Alexandra Shevchenko, she was one of the founders of the feminist activist group FEMEN, which publicly demonstrates in various countries against sexual exploitation, income inequality, and policies of the Roman Catholic Church, among other causes.

Boris Spiegel is a Russian politician and businessman. Haaretz describes him as an oligarch who is "closely tied to the Kremlin." From 2003 to 2013, he has represented Penza Oblast in the Russian Federation Council; in December 2011, he was appointed the First Deputy Chairman of the Committee on Constitutional Legislation, Legal and Judicial Affairs and Civil Society Development.

Alexander Vladimirovich Rutskoy is a Russian politician and a former Soviet military officer, Major General of Aviation (1991). He served as the only Vice President of Russia from 10 July 1991 to 4 October 1993 and as the Governor of Kursk Oblast from 1996 to 2000. In September 1993 Rutskoy was proclaimed the Acting President of Russia following Boris Yeltsin's impeachment which led to the Russian constitutional crisis of 1993 where he played one of the key roles.

Nachman of Breslov, also known as Reb Nachman of Bratslav, Reb Nachman Breslover, Nachman from Uman, was the founder of the Breslov Hasidic movement.

Arkady Semyonovich Ukupnik is a Russian composer, pop singer, actor, and producer.

Iryna Oleksiyivna Merleni, née Melnyk (Мельник), married name Mykulchyn (Микульчин) is a Ukrainian wrestler, who competed in the – 48 kg weight class at the 2004 Summer Olympics and claimed the gold medal. In the same event at the 2008 Summer Olympics, she won a bronze medal. She is a three-time world champion, and won the European championship once.

Moshé Pinchas Feldenkrais was a Ukrainian-Israeli engineer and physicist, known as the founder of the Feldenkrais Method, a system of physical exercise that aims to improve human functioning by increasing self-awareness through movement.

Samuel Mitja Rapoport was a Ukrainian-born German university professor of biochemistry in East Germany. Of Jewish descent and a committed communist, he fled Austria after its annexation by Nazi Germany, and moved to the United States. In 1950, as a result of an investigation of un-American activities, he was offered a professorship in East Berlin. He was married to the renowned pediatrician Ingeborg Rapoport.