List of Famous people born in Guadalajara, Mexico

Guillermo del Toro Gómez is a Mexican filmmaker, author, actor, and former special effects makeup artist. He is best known for the Academy Award-winning fantasy films Pan's Labyrinth (2006) and The Shape of Water (2017), winning the Oscars for Best Director and Best Picture for the latter.

Javier Hernández Balcázar is a Mexican professional footballer who plays as a striker for Major League Soccer club LA Galaxy and the Mexico national team. Hernández is commonly known by his nickname, Chicharito, which he wears on his shirt.

Francisco Guillermo Ochoa Magaña, commonly referred to as Memo, is a Mexican professional footballer who plays as a goalkeeper for Liga MX club América and the Mexico national team.

María Cristina Estela Marcela Jurado García, better known as Katy Jurado, was a Mexican actress of film, television, and theater. Jurado began her acting career in Mexico. She achieved some renown in her country's cinema during the period known as the Golden Age of Mexican cinema (1940s–1950s). In 1951, she was discovered by American filmmakers in Mexico and began her Hollywood career. She acted in notable Western films of the 1950s and 1960s. An exotic beauty, Jurado specialized in interpretations of complex, stereotyped and sexualized women. Her talent for playing a variety of characters helped pave the way for Mexican actresses in American cinema. She was the first Latin American actress nominated for an Oscar, as Best Supporting Actress for her work in Broken Lance (1954), and was the first to win a Golden Globe Award, for her performance in High Noon (1952).

Gael García Bernal is a Mexican actor and producer. García Bernal is best known for his performances in the films Bad Education, The Motorcycle Diaries, Amores perros, Y tu mamá también, Babel, and Coco, and for his role as Rodrigo de Souza in the Amazon Studios' web television series Mozart in the Jungle. He and Diego Luna founded Canana Films in Mexico City.

José Andrés Guardado Hernández is a Mexican professional footballer who plays for Spanish club Real Betis and captains the Mexico national team. Mainly a midfielder, he can also operate as a left winger or left-back.

Vicente "Chente" Fernández Gómez is a Mexican retired singer, actor, and film producer. Nicknamed "El Rey de la Música Ranchera", Fernández started his career as a busker, and has since become a cultural icon, recording more than 50 albums and contributing to more than 30 films. His repertoire consists of rancheras and other Mexican classics. He is accompanied live by a mariachi group, but he is not technically a mariachi musician, as he only sings live. Vicente's fame rose after the death of Javier Solís.

Karen Alexa Grasso Montes, better known as Alexa Grasso, is a Mexican mixed martial artist who competes in the flyweight division. She is currently signed with the Ultimate Fighting Championship (UFC). As of January 19, 2021, she is #15 in the UFC women's flyweight rankings.

Enrique Álvarez Félix was a Mexican actor, known for his roles in telenovelas and in films, such as The Monastery of the Vultures and The House of the Pelican.

Gerardo Murillo Cornado, also known by his signature "Dr. Atl", was a Mexican painter and writer.