List of Famous people born in Epirus Region, Greece

Karolos Papoulias is a Greek politician who served as President of Greece from 2005 to 2015. A member of the Panhellenic Socialist Movement (PASOK), he previously was Minister of Foreign Affairs from 1985 to 1989 and again from 1993 until 1996.

Vassiliki Kontaxi, nicknamed Kyra Vassiliki, was an influential Greek woman brought up in the seraglio of the Ottoman ruler Ali Pasha.

Antonis Nikopolidis is a Greek former footballer who played as a goalkeeper, and former manager of the Greece national under-21 football team.

Giannis Anastasiou is a Greek professional football manager and former player, who is the current manager of Super League club Panetolikos.

Giannis Tatsis is a Greek retired football midfielder and manager.

Athanasia Tsoumeleka is a Greek race walker, who won a gold medal at the 2004 Summer Olympics in Athens.

Konstantinos Dovas was a Greek general and interim Prime Minister.

Parthenius I of Constantinople, was the Patriarch of the Church of Constantinople from 1639 to 1644. Parthenius was patriarch during a period of frequent changes of the occupant of the cathedra of Constantinople under the Ottoman Sultan. He only served one period.