List of Famous people born in Centre-Val de Loire, France

Robert Massin was a French graphic designer, art director and typographer, notable for his innovative experimentation with expressive forms of typographic composition. Massin stopped using his first name in the 1950s.

Frédéric Vitoux is a French writer and journalist.

Bernard Boucault is a French public official. He was previously director of the École nationale d'administration. He was head of the Paris police from 2012 until 2015. He has been involved in several high-profile police actions, involving protestors in 2013 and the Football Championship of France concerning Paris Saint-Germain F.C. in 2013.

Florian Rousseau is a former French track cyclist who won three gold medals and one silver at the Summer Olympics. He was popular among spectators for the facial expressions he pulled - many of them seeming to make his eyes bulge - to help him concentrate at the start of races. In retirement he became one of France's national sprint coaches.

Ève Brenner is a French opera singer notable for her voice which could cover five octaves. She has two children, the singer Aude Brenner, and film director Gilles Paquet-Brenner.

Charles I d'Amboise was a French politician and military figure, a member of the House of Amboise. He was lord of Chaumont-sur-Loire, Sagonne, Meillant, Charenton-du-Cher. Louis XI appointed him governor of Île-de-France, Champagne and Burgundy. He was admitted to the order of Saint Michael.

Nicolas Jean-Christophe Escudé is a former professional tennis player from France, who turned professional in 1995. He won four singles titles and two doubles titles during his career.

Yolanda of Courtenay, was a Queen of Hungary as the second wife of King Andrew II of Hungary.

Marion Sicot is a French professional racing cyclist, who last rode for UCI Women's Team Doltcini–Van Eyck Sport during the 2019 women's road cycling season.

Bernard Bigot is an academic, civil servant, and the Director-General of the ITER organization since 2015.