List of Famous people born in Castile and León, Spain

Pedro Segura y Sáenz was a Spanish Cardinal of the Roman Catholic Church who served as Archbishop of Toledo from 1927 to 1931, and Archbishop of Seville from 1937 until 1954. Segura was elevated to the cardinalate in 1927.

Julián Barrio Barrio is a Spanish prelate of the Roman Catholic Church. Since January 1996, he has served as Archbishop of Santiago de Compostela.

Laudelino Cubino González is a Spanish former professional road racing cyclist. He was born in Béjar, Spain.

Moisés Dueñas Nevado is a Spanish former road racing cyclist, who competed professionally between 2002 and 2009, and then again from 2012 to 2015.

Juan Carlos Domínguez Domínguez is a former professional road racing cyclist. He was a professional rider from 1995 to 2006.

Pablo Fernando Puente Aparicio was a Spanish architect and university professor. He was known, among other professional work, for being the architect of the first nine editions of the famous exhibition "Las Edades del Hombre" and for his teaching work at the Higher Technical School of Architecture of Valladolid (ETSAV).