List of Famous people who are 81

Luciana Maria Arrighi is a Brazilian-born, Australian-raised, Italian production designer. She won an Oscar for the film Howards End in the category Best Art Direction.

Thomas Michael O'Neil is an American physicist who specializes in plasma physics.

James Henry Binford "Binnie" Peay III is a retired four-star general of the United States Army. He served as the 14th superintendent of the Virginia Military Institute from 2003-2020, and as chairman of the Allied Defense Group from 2001-03. He has also served on various corporate and nonprofit boards.

Sir John Chippendale "Chips" Lindley Keswick is a British merchant banker and member of the Keswick family who control Jardine Matheson, founded by William Jardine. He was chairman of Arsenal Football Club from June 2013 until his retirement in May 2020.

André-Joseph Léonard is a Belgian prelate who served as the Archbishop of Mechelen-Brussels and Primate of Belgium after his installation on 27 February 2010. He had previously served as Bishop of Namur from 1991 until 2010 under the name André-Mutien Léonard. Pope Francis accepted his resignation on 1 June 2015.

Arieh Warshel is an Israeli-American biochemist and biophysicist. He is a pioneer in computational studies on functional properties of biological molecules, Distinguished Professor of Chemistry and Biochemistry, and holds the Dana and David Dornsife Chair in Chemistry at the University of Southern California. He received the 2013 Nobel Prize in Chemistry, together with Michael Levitt and Martin Karplus for "the development of multiscale models for complex chemical systems".

Aleksandr Sergeyevich Ivanchenkov is a retired Soviet cosmonaut who flew as Flight Engineer on Soyuz 29 and Soyuz T-6, he spent 147 days, 12 hours and 37 minutes in space.

Jan David Simon, 3rd Viscount Simon is a British peer.