List of Famous people born in Valparaíso Region, Chile

Matías Novoa, is a Chilean-Mexican actor and model. He is best known for working with TV Azteca doing telenovela.

Esteban Andrés Carvajal Tapia is a Chilean footballer that currently plays for Palestino as a defensive midfielder.

Alejandra Matus Acuña is a Chilean journalist and writer. In 1999 she published El libro negro de la justicia chilena. The available copies of the book were confiscated one day before the planned release and Matus was accused by Servando Jordán, minister of the Supreme Court of Chile, of the delict of "desacato" ("contempt") invoking the article 6-B of the Ley de Seguridad del Estado. This prompted Matus to apply for—and receive—political asylum in the United States. The case led to the "desacato" article to be removed from the law with the new Ley de Prensa that was signed on May 25 of 2001 which allowed Matus to return to Chile. Despite the new law the book continued to be banned until October 2001 when the Corte de Apelaciones removed the ban.

Evelyn Felisa Ankers was an American actress who often played variations on the role of the cultured young leading lady in the many American horror films during the 1940s, most notably The Wolf Man (1941) opposite Lon Chaney Jr., a frequent screen partner.

José Luis Cabión Dianta is Chilean footballer who plays for Deportes Melipilla as midfielder.

Fernando Cordero Rusque was a Chilean military officer and politician who served as the General Director of Carabineros and as a Senator.

Raúl Pedro Sánchez Soya was a Chilean football defender who played for Chile in the 1962 FIFA World Cup. He also played for Santiago Wanderers, Everton and Colo-Colo.

John Christian Watson, commonly known as Chris Watson, was an Australian politician who served as the third Prime Minister of Australia. He was the first Prime Minister from the Australian Labour Party, and led the world's first Labour Party government, From paternal German and maternal British ancestry, he is the only Australian Prime Minister not born in a Commonwealth country.

Laura Allende Gossens was a Chilean politician, a member of the lower chamber of parliament and sister of former president of Chile Salvador Allende.

Manuel Francisco Antonio Julián Montt Torres was a Chilean statesman and scholar. He was twice elected President of Chile between 1851 and 1861.