List of Famous people born in Trenčín Region, First Czechoslovak Republic

Ľudovít Velislav Štúr, known in his era as Ludevít Štúr, was a Slovakian revolutionary politician and writer. As a leader of the Slovak national revival in the 19th century, and the author of the Slovak language standard, he is lauded as one of the most important figures in Slovak history.

Barbara Zápolya (1495–1515) was Queen of Poland and Grand Duchess of Lithuania as the first wife of King Sigismund I the Old. Marriage to Barbara represented an alliance between Sigismund and the House of Zápolya against the Habsburgs in succession disputes over the throne to the Kingdom of Hungary. The alliance was short-lived as the renewed Muscovite–Lithuanian War forced Sigismund to look for Habsburg allies. The marriage was loving, but short. Barbara was the mother of Hedwig, Electress of Bradenburg, but died soon after the birth of her second daughter Anna.

Miroslav Hlinka was a Slovak professional ice hockey player and assistant coach.

Marcel Hossa is a Slovak former professional ice hockey left winger. Hossa previously played in the National Hockey League (NHL) with the Montreal Canadiens, New York Rangers and Phoenix Coyotes, having been drafted by the Canadiens in the first round, 16th overall, in the 2000 NHL Entry Draft.

Kristína Gavnholt is a Czech badminton player. She competed for Czech Republic at the 2008, 2012 and 2016 Summer Olympics.

Ján Svorada is a retired Slovak and Czech road racing cyclist. Svorada was born in Czechoslovakia; when that country split up in 1993, Svorada raced for Slovakia until 1996, when he started racing for the Czech Republic.

Miloslav Mečíř is a former professional tennis player from Slovakia. He won the men's singles gold medal at the 1988 Olympic Games, where he represented Czechoslovakia, and played in two Grand Slam singles finals. In 1987 he won the WCT Finals, the season-ending championship for the World Championship Tennis tour.

Jozef Feranec was a Slovak Roman Catholic bishop.

Ernest Nagel was an American philosopher of science. Along with Rudolf Carnap, Hans Reichenbach, and Carl Hempel, he is sometimes seen as one of the major figures of the logical positivist movement. His 1961 book The Structure of Science is considered a foundational work in the logic of scientific explanation.