List of Famous people born in Region of Murcia, Spain

Carlos Alcaraz Garfia is a Spanish tennis player. Alcaraz has a career high ATP singles ranking of 136 achieved on 19 October 2020.At the age of 16, Alcaraz made his ATP main draw debut at the 2020 Rio Open, defeating fellow countryman Albert Ramos Viñolas, 7–6^(7–2), 4–6, 7–6^(7–2), in three hours and 36 minutes, after receiving a wildcard for the singles main draw.

Jaime Lorente López, is a Spanish actor. He is best known for playing the roles of Daniel "Denver" Ramos in Money Heist and Fernando "Nano" García Domínguez in Élite.

Rafael "Rafa" Mir Vicente is a Spanish professional footballer who plays as a forward for Huesca on loan from English club Wolverhampton Wanderers.

Adriana Torrebejano Giménez is a Spanish actress.

Pedro Acosta is a Spanish motorcycle racer.

Ruth Lorenzo Pascual, better known as Ruth Lorenzo, is a Spanish singer and composer, best known for coming fifth in the fifth series of the British TV talent show The X Factor in 2008. She represented Spain in the Eurovision Song Contest 2014 with the song "Dancing In The Rain", which entered the Spanish Singles Chart at number 5. She scored 74 points for Spain, finishing in 10th place.

Alejandro Valverde Belmonte is a Spanish road racing cyclist, who currently rides for UCI WorldTeam Movistar Team. Valverde's biggest wins have been the Vuelta a España in 2009, Critérium du Dauphiné in 2008 and 2009, Tour of the Basque Country in 2017, Volta a Catalunya in 2009, 2017 and 2018, Liège–Bastogne–Liège in 2006, 2008, 2015 and 2017, La Flèche Wallonne in 2006, 2014, 2015, 2016 and 2017, the Clásica de San Sebastián in 2008 and 2014, the 2006 and 2008 UCI ProTours, the 2014 and 2015 UCI World Tours, and the road race in the 2018 World Championships.

Pedro León Sánchez Gil, known as León, is a Spanish footballer who plays for SD Eibar as a right winger.

Javier Calvo Guirao is a Spanish actor, stage director, and film director. He is the best known for his role of Fernando "Fer" Redondo in the Antena 3 series Física o Química and for creating and directing the musical La llamada together with Javier Ambrossi, as well as co-directing its film adaptation.

Marta Nieto is a Spanish actress.