List of Famous people born in Prešov Region, First Czechoslovak Republic

Jozef Kožlej is a retired Slovak international professional footballer who played for clubs in Czechoslovakia, Germany, Greece and Cyprus.

Marcel Palonder is a Slovak singer. He represented his country in the Eurovision Song Contest 1996 with the song "Kým nás máš". His song qualified from the semifinal, earning 36 points but in the final it placed 17th place with 19 points. The points to the Slovak entry were given by: Greece four points, Malta eight points, Poland five points and Spain two points.

Dr. Ágoston Trefort was a Hungarian politician, who served as Minister of Religion and Education from 1872 until his death. He was the President of the Hungarian Academy of Sciences from 1885.

Joseph Petzval was a mathematician, inventor, and physicist best known for his work in optics. He was born in the town of Szepesbéla in the Kingdom of Hungary.

Ŝtephen Sečka was a Slovak Roman Catholic bishop.

Milan Chautur, C.Ss.R. is a Slovak Greek Catholic hierarch, who has served as the first Eparchial Bishop of the newly created Slovak Catholic Eparchy of Košice since 30 January 2008. Previously he was an Auxiliary Bishop of the Slovak Catholic Eparchy of Prešov from 11 January 1992 until 27 January 1997 and as Apostolic Exarch of the Apostolic Exarchate of Košice from 29 January 1997 until 30 January 2008.

Count Emil Dessewffy de Csernek et Tarkeő was a Hungarian conservative politician, leader of the Conservative Party, who served as President of the Hungarian Academy of Sciences from 1855 until his death.