List of Famous people born in Phra Nakhon Si Ayutthaya, Thailand

Phra Phutthayotfa Chulalok Maharaj, born Thongduang and also known as Rama I, was the founder of Rattanakosin Kingdom and the first monarch of the reigning Chakri dynasty of Siam. His full title in Thai is Phra Bat Somdet Phra Paramoruracha Mahachakkriborommanat Phra Phutthayotfa Chulalok. He ascended the throne in 1782, after defeating a rebellion which had deposed King Taksin of Thonburi. He was also celebrated as the founder of Rattanakosin as the new capital of the reunited kingdom.

Taksin or the King of Thonburi was the only King of the Thonburi Kingdom. He had been an Ekatat servant and then was a leader in the liberation of Siam from Burmese occupation after the Second Fall of Ayutthaya in 1767, and the subsequent unification of Siam after it fell under various warlords. He established the city of Thonburi as the new capital, as the city of Ayutthaya had been almost completely destroyed by the invaders. His reign was characterized by numerous wars; he fought to repel new Burmese invasions and to subjugate the northern Thai kingdom of Lanna, the Laotian principalities, and a threatening Cambodia.

Thawan Thamrongnawasawat, born Thawan Tharisawat, was the eighth Prime Minister of Thailand from 1946–1947. Before becoming a politician, he was a naval officer, holding the rank of rear admiral.

Somdet Phra Bawornrajchao Maha Sura Singhanat (1744–1803) was the younger brother of Phutthayotfa Chulalok, the first monarch of the Chakri dynasty of Siam. As an Ayutthayan general, he fought alongside his brother in various campaigns against Burmese invaders and the local warlords. When his brother crowned himself as the king of Siam at Bangkok in 1781, he was appointed the Front Palace or Maha Uparaj, the title of the heir. During the reign of his brother, he was known for his important role in the campaigns against Bodawpaya of Burma.

Ramrachathirat was a king of Ayutthaya, an ancient kingdom in Thailand.

Ekkathat or Borommoracha III or King of Suriyamarin Throne Hall was the 6th monarch of the Ban Phlu Luang dynasty, the 33rd and the last monarch of Ayutthaya Kingdom, ruling from 1758 to 7 April 1767 prior to the fall of the kingdom. Moreover, he was called by the people at the time being that "King Khiruean", meaning "the king with skin disease"; because he had chloasma.