List of Famous people born in Pennsylvania, United States of America

James Pollard Espy was a U.S. meteorologist. Espy developed a convection theory of storms, explaining it in 1836 before the American Philosophical Society and in 1840 before the French Académie des Sciences and the British Royal Society. His theory was published in 1840 as The Philosophy of Storms. He became meteorologist to the War (1842) and Navy (1848) departments and developed the use of the telegraph in assembling weather observation data by which he studied the progress of storms and laid the basis for scientific weather forecasting.

Kenneth Edward Macha is a former Major League Baseball third baseman and manager. He managed the Oakland Athletics from 2003–2006, including American League Western Division championships in both his first and final seasons with the team, and later managed the Milwaukee Brewers (2009–10).

Molly Bair is an American model, best known for her appearances in the Spring/Summer 2015 fashion shows.

Thomas Wiltberger Evans was an American dentist. He performed dental procedures on many heads of state, including Napoleon III, and received numerous medals for his dentistry, including the Grand Croix of the Légion d'honneur. He is noted for popularizing a number of techniques that have since become standard, including the use of amalgam fillings and of nitrous oxide.

Major Andrew Henry was an American miner, army officer, frontiersman, trapper and entrepreneur. Alongside William H. Ashley, Henry was the co-owner of the highly successful Rocky Mountain Fur Company, otherwise known as "Ashley's Hundred", for the famous mountain men working for their firm from 1822 to 1832. Henry appears in the narrative poem the Song of Hugh Glass, which is part of the Neihardt's Cycle of the West. He is portrayed by John Huston in the 1971 film Man in the Wilderness and by Domhnall Gleeson in the 2015 film The Revenant, both of which depict Glass's bear attack and journey.

Monica Byrne is an American playwright and science fiction author. She is best known for her drama What Every Girl Should Know and her debut novel The Girl in the Road, which won the 2015 James Tiptree, Jr. Award and was nominated for the Locus and Kitschies awards.

Katherine Mayo was an American historian and nativist. Mayo entered the public sphere as a political writer advocating American nativism, opposition to non-white and Catholic immigration to the United States, along with promoting racist stereotypes of African Americans. She became known for denouncing the Philippine Declaration of Independence on racialist and religious grounds, and then went on to publish and promote her best-known work, Mother India (1927), a deeply critical book on Indian society, religion and culture. Written in opposition to the Indian independence movement, the book received a sharply divided reception upon its publication and was accused by several authors of being Indophobic, including Mahatma Gandhi.

Kitty Kallen was an American popular singer whose career spanned from the 1930s to the 1960s, to include the Swing era of the Big Band years, the post-WWII pop scene and the early years of rock 'n roll. Kallen performed with popular big band leaders of the 1940s, including Jimmy Dorsey and Harry James, before establishing a solo career.

Horace Trumbauer was a prominent American architect of the Gilded Age, known for designing residential manors for the wealthy. Later in his career he also designed hotels, office buildings, and much of the campus of Duke University. Trumbauer's massive palaces flattered the egos of his "robber baron" clients, but were dismissed by his professional peers. His work made him a wealthy man, but his buildings rarely received positive critical recognition. Today, however, he is hailed as one of America's premier architects, with his buildings drawing critical acclaim even to this day.

Joseph Albert Walker was an American World War II pilot, experimental physicist, NASA test pilot, and astronaut. He was one of twelve pilots who flew the North American X-15, an experimental spaceplane jointly operated by the Air Force and NASA.