List of Famous people born in Pennsylvania, United States of America

William Larimer "Larry" Mellon Jr. (1910–1989) was an American philanthropist and physician.

John Warhola played a pivotal role in maintaining the legacy of his younger brother, pop artist Andy Warhol, assigned responsibility by their father on his deathbed to ensure that Andy attended college and serving as a trustee of the Andy Warhol Foundation for the Visual Arts after his brother's death in 1987. Warhola oversaw the establishment of The Andy Warhol Museum in Pittsburgh and the Andy Warhol Museum of Modern Art in Medzilaborce, Slovakia.

Donna Lee Butterworth was an American actress, best known for starring opposite Elvis Presley in the 1966 musical comedy Paradise, Hawaiian Style, when she was 10 years old.

Ailsa Mellon Bruce was a prominent American socialite and philanthropist who established the Avalon Foundation.

Titian Ramsay Peale was an American ornithologist, entomologist, photographer, and explorer from Philadelphia, Pennsylvania. He was a scientific illustrator whose paintings and drawings of wildlife were known for their beauty and accuracy.

Adolphe Jean Menjou was an American actor. His career spanned both silent films and talkies. He appeared in such films as Charlie Chaplin's A Woman of Paris, where he played the lead role; Stanley Kubrick's Paths of Glory with Kirk Douglas; Ernst Lubitsch's The Marriage Circle; The Sheik with Rudolph Valentino; Morocco with Marlene Dietrich and Gary Cooper; and A Star Is Born with Janet Gaynor and Fredric March, and was nominated for an Academy Award for The Front Page in 1931.

Marianne Wiggins is an American author. The characters and storylines in her novels have been described as unusual. According to The Cambridge Guide to Women's Writing in English, Wiggins writes with "a bold intelligence and an ear for hidden comedy." She has won a Whiting Award, an National Endowment for the Arts award and the Janet Heidinger Kafka Prize. She was a finalist for the Pulitzer Prize in fiction in 2004 for her novel Evidence of Things Unseen.

Colonel John William Russell was an American equestrian who won a bronze medal at the 1952 Summer Olympics in Helsinki, Finland. After serving in the United States Army during World War II, he began competing in international equestrian tournaments and was eventually selected to join the United States team at the 1948 Summer Olympics in London. After his success at the 1952 edition, he continued to participate in events around the world, but military duties and a broken bone in his horse caused him to miss the 1956 Summer Olympics. He retired from active competition that year and became the head of United States Modern Pentathlon Training Center, where he coached six United States Olympic modern pentathlon delegations, twenty-two World Championship teams, and helped organize two World Modern Pentathlon Championships. He retired and opened the Russell Equestrian Center and was inducted into the United States Show Jumping Hall of Fame in 2001.