List of Famous people born in Ōsaka Prefecture, Japan

Naomi Osaka is a Japanese professional tennis player. Osaka has been ranked No. 1 by the Women's Tennis Association (WTA), and is the first Asian player to hold the top ranking in singles. She is a three-time Grand Slam singles champion, and is the reigning champion at the US Open. Her six WTA titles on the WTA Tour also include two at the Premier Mandatory level. At the 2018 US Open and the 2019 Australian Open, Osaka won her first two Grand Slam singles titles in back-to-back Grand Slam tournaments, and is the first player to achieve this feat since Jennifer Capriati in 2001.

Taishō Sugō , known professionally as Masaki Suda , is a Japanese actor and singer. He played Philip in Kamen Rider W. He won the Japan Academy Film Prize for Outstanding Performance by an Actor in a Leading Role. His debut song is "Mita Koto mo Nai Keshiki."

Kenjiro Tsuda is a Japanese actor, voice actor, narrator, and film director. He works at Amuleto. Some of his roles as a voice actor: Seto Kaiba in Yu-Gi-Oh!, Sadahara Inui in Shin Tennis no Ouji-sama, Kazama Chikage in Hakuoki, Mikoto Suoh and Gouki Zenjou in K Project, Fire Emblem in Tiger & Bunny, Nicolas Brown in Gangsta, Doug Horbat in Juushinki Pandora, Atomic Samurai in One-Punch Man, Overhaul in My Hero Academia, Matoba Kei in Cop Craft, Lero Ro in Tower of God, Shiori Ichinose in Tokunana, Nino in ACCA, Hakuto Kunai in Maou-sama, Retry!, Akihito Narihisago/Sakaido in ID:INVADED, Manji in Mugen no Juunin and Nanami Kento in Jujutsu Kaisen.

Takumi Minamino is a Japanese professional footballer who plays as an attacking midfielder or winger for Premier League club Liverpool and the Japan national team.

Yuri Nakamura is a Japanese actress and former singer. Her real name is Yuri Sei or Woori Song.

Farid Yu Darvishsefat , popularly known as Yu Darvish, is a Japanese professional baseball starting pitcher for the San Diego Padres of Major League Baseball (MLB). Darvish has also played in MLB for the Texas Rangers, Los Angeles Dodgers and Chicago Cubs and in Nippon Professional Baseball for the Hokkaido Nippon-Ham Fighters. In international play, Darvish pitched in the 2008 Beijing Olympics and the 2009 World Baseball Classic as a member of the Japanese national team.

Jun Murakami is a Japanese actor. He is not to be confused with Japanese stunt actor Jun Murakami.

Takashi Tachibana is a social activist, journalist, accountant and politician who is the founder and leader of The Party to Protect the People from NHK . A former assemblyman for the Funabashi City Assembly and the Katsushika Ward Assembly, he was elected to the House of Councillors in the July 2019 regular election on his party's proportional representation list. He automatically forfeited his seat on 10 October when he officially became a candidate in the October 2019 by-election to the House of Councillors for a majoritarian seat in Saitama.

Junichi Okada is a member of Japanese boy band V6, which is under the management of Johnny & Associates. He joined Johnny & Associates at the age of 14.

Hirofumi Yoshimura is a Japanese politician currently serving as the Governor of Osaka Prefecture. He assumed office in April 2019.