List of Famous people born in Ontario, Canada

Ante Josip "Tony" Mandarich is a Canadian former American football offensive tackle who played in the National Football League (NFL) for seven seasons. He was drafted in the first round of the 1989 NFL Draft by Green Bay Packers as the second overall pick and also played for the Indianapolis Colts.

Connor Andrew McDavid is a Canadian professional ice hockey centre and captain of the Edmonton Oilers of the National Hockey League (NHL). He is considered to be one of the best players in the world by many colleagues and members of the news media.

Tessa Jane McCormick Virtue is a Canadian retired ice dancer. With ice dance partner Scott Moir, she is the 2010 and 2018 Olympic champion, the 2014 Olympic silver medallist, a three-time World champion, a three-time Four Continents champion, the 2016–17 Grand Prix Final champion, an eight-time Canadian National champion, the 2006 World Junior champion and the 2006 Junior Grand Prix gold medallists. Virtue and Moir are also the 2018 Olympic gold medallists in the team event and the 2014 Olympic silver medallists in the team event. They are the most decorated Canadian ice dance team of all time and the most decorated Olympic figure skaters of all time. They are also the only ice dancers in history to achieve a Career Super Grand Slam by winning all three major senior competitions, the two major junior competitions and the Olympics over the course of their careers.

Sir Frederick Grant Banting was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential.

Denise Katherine Matthews, better known as Vanity, was a Canadian singer, songwriter, dancer, model, and actress who turned away from her music and acting career to concentrate on evangelism. Her career lasted from the early 1980s until the early/mid-1990s. She was the lead singer of the female trio Vanity 6 from 1981 until it disbanded in 1983. They are known for their 1982 pop hit "Nasty Girl". Vanity's music career also included two solo albums on the Motown Records label, Wild Animal and Skin on Skin, as well as the minor hit singles "Pretty Mess", "Mechanical Emotion", "Undress", and "Under the Influence". She also had a successful film career, starring in the movies The Last Dragon, 52 Pick-Up, and Action Jackson. Throughout the 1980s and early 1990s, Vanity appeared in many magazines around the world. She died on February 15, 2016, at the age of 57, due to kidney failure.

Robert Patrick Amell IV is a Canadian-American actor and producer. He is known for playing Stephen Jameson on The CW series The Tomorrow People, Ronnie Raymond/Firestorm on The CW series The Flash, Nathan Brown on Upload, Fred Jones in the films Scooby-Doo! The Mystery Begins and Scooby-Doo! Curse of the Lake Monster, and the films The Hunters as Paxton Flynn, The DUFF as Wesley Rush, and The Babysitter as Max. He has also had recurring roles on television shows such as Life with Derek, True Jackson, VP, Unnatural History, and Revenge.

Neil Ellwood Peart OC was a Canadian musician, songwriter, and author, best known as the drummer and primary lyricist of the rock band Rush. Peart earned numerous awards for his musical performances, including an induction into the Modern Drummer Readers Poll Hall of Fame in 1983, making him the youngest person ever so honoured. Known to fans by the nickname 'The Professor', his drumming was renowned for its technical proficiency and his live performances for their exacting nature and stamina.

Gordon Edgar Downie was a Canadian rock singer-songwriter, musician, writer and activist. He was the lead singer and lyricist for the Canadian rock band The Tragically Hip, which he fronted from its formation in 1984 until his death in 2017. He is widely regarded as one of the most influential and popular artists in Canadian music history.

Maitreyi Ramakrishnan is a Canadian actress of Tamil Sri Lanka origin known for her leading role in the Netflix teen comedy series Never Have I Ever (2020).

Katherine Louisa Ryan is a Canadian comedian, writer, presenter and actress based in the United Kingdom.