List of Famous people born in Makkah Region, Saudi Arabia

Talal bin Abdulaziz Al Saud, formerly also called The Red Prince, was a Saudi Arabian politician, dissident, businessman, and philanthropist. A member of the House of Saud, he was notable for his liberal stance, striving for a national Constitution, the full rule of law and equality before the law. He was also the leader of Free Princes Movement in the 1960s.

Nura Habib Omer is a German rapper of Saudi-Arabian and Eritrean descent.
She is known for being part of Die toten Crackhuren im Kofferraum and SXTN. Following the split of SXTN in 2018, she has pursued a solo career.

Loujain al-Hathloul is a Saudi women's rights activist, a social media figure, and a political prisoner. She is a graduate of the University of British Columbia. Al-Hathloul has been arrested and released on several occasions for defying the ban on women driving in Saudi Arabia and was arrested in May 2018, with several prominent women's rights activists, on the charge of "attempting to destabilise the kingdom" after being effectively kidnapped in the United Arab Emirates (UAE). As of October 2018, her husband, Saudi stand-up comedian Fahad al-Butairi, had also been forcefully returned from Jordan to the Kingdom and was under arrest.

ʿAbd al-ʿUzzā ibn ʿAbd al-Muṭṭalib , often known as Abū Lahab was Muhammad's half paternal uncle. He was one of the Meccan Quraysh leaders who opposed Muhammad and his followers and was condemned in the surah Lahab of the Quran for antagonizing Islam.

Al-Mukhtar ibn Abi Ubayd Al-Thaqafi was a pro-Alid revolutionary based in Kufa, who led a rebellion against the Umayyad Caliphate in 685 and ruled over most of Iraq for eighteen months during the Second Fitna.

Bandar bin Sultan Al Saud is a member of the House of Saud and was Saudi Arabia's ambassador to the United States from 1983 to 2005. From 2005 to 29 January 2015 he served as secretary general of the National Security Council, and was director general of the Saudi Intelligence Agency from 2012 to 2014. On 1 July 2014 he was appointed King Abdullah's special envoy which lasted until 29 January 2015.

Zubayr ibn al-ʿAwwām was an Arab Muslim commander in the service of the Islamic prophet Muhammad and the caliphs Abu Bakr and Umar who played a leading role in the Ridda Wars against rebel tribes in Arabia in 632–633 and later participated in early Muslim conquests of Sasanian Iraq in 633–634, Byzantine Syria in 634–638, and the Exarchate of Africa in 639–643.

Uqba ibn Nafi ibn Abd al-Qays al-Fihri al-Qurashi was an Arab general serving the Rashidun Caliphate since the Reign of Umar and later on the Umayyad Caliphate during the reigns of Muawiyah I and Yazid I, leading the Muslim conquest of the Maghreb, including present-day Algeria, Tunisia, Libya and Morocco.

ʿAbd Allāh ibn ʿUmar ibn al-Khaṭṭāb was companion of the Islamic prophet Muhammad and son of the second Caliph Umar. He was a prominent authority in hadith and law. He remained neutral during the events of the first Fitna (656–661).

Umm Salama Hind bint Abi Umayya, also known as Hind al-Makhzumiyah or Hind bint Suhayl was one of Muhammad's wives. Umm Salama was her kunya meaning, "mother of Salama". Umm Salama was one of the most influential wives of Muhammad, recognized largely for recalling numerous Hadiths, or stories about Muhammad. The Shia belief is that Umm Salama was the second-most important wife of Muhammad after Khadija.