List of Famous people born in Holy Roman Empire

Jan van Eyck was a painter active in Bruges who was one of the early innovators of what became known as Early Netherlandish painting, and one of the most significant representatives of Early Northern Renaissance art. The surviving records indicate that he was born around 1380–1390, most likely in Maaseik, in present-day Belgium. He took employment in the Hague around 1422 when he was already a master painter with workshop assistants, and was employed as painter and valet de chambre with John III the Pitiless, ruler of Holland and Hainaut. After John's death in 1425, he was later appointed as court painter to Philip the Good, Duke of Burgundy, working in Lille until he moved to Bruges in 1429 where he lived until his death. He was highly regarded by Philip and undertook a number of diplomatic visits abroad, including to Lisbon in 1428 to explore the possibility of a marriage contract between the duke and Isabella of Portugal.

Mechthild of Magdeburg, a Beguine, was a Christian medieval mystic, whose book Das fließende Licht der Gottheit is a compendium of visions, prayers, dialogues and mystical accounts. She was the first mystic to write in German.

Louis III, was an Elector Palatine of the Rhine from the house of Wittelsbach in 1410–1436.

Stephen of Simmern-Zweibrücken was Count Palatine of Simmern and Zweibrücken from 1410 until his death in 1459.

Oddantonio da Montefeltro was the first duke of Urbino in Italy.

Barthélemy d'Eyck, van Eyck or d' Eyck, was an Early Netherlandish artist who worked in France and probably in Burgundy as a painter and manuscript illuminator. He was active between about 1440 to about 1469. Although no surviving works can be certainly documented as his, he was praised by contemporary authors as a leading artist of the day, and a number of important works are generally accepted as his. In particular, Barthélemy has been accepted by most experts as the artists formerly known as the Master of the Aix Annunciation for paintings, and the Master of René of Anjou for illuminated manuscripts. He is thought by many to be the Master of the Shadows responsible for parts of the calendar of the Très Riches Heures du Duc de Berry.