List of Famous people born in Central Denmark Region, Kingdom of Denmark

Bjarne Lykkegård Riis, nicknamed The Eagle from Herning, is a Danish former professional road bicycle racer who placed first in the 1996 Tour de France. For many years he was the owner and later manager of Russian UCI WorldTeam Tinkoff–Saxo. Other career highlights include placing first in the Amstel Gold Race in 1997, multiple Danish National Championships, and stage wins in the Giro d'Italia. On 25 May 2007, he admitted that he placed first in the Tour de France using banned substances, and he was no longer considered the winner by the Tour's organizers. In July 2008, the Tour reconfirmed his victory but with an asterisk label to indicate his doping offences.

Henrik Toft Hansen is a Danish handball player for Paris Saint-Germain and the Danish national team.

Schack August Steenberg Krogh was a Danish professor at the department of zoophysiology at the University of Copenhagen from 1916 to 1945. He contributed a number of fundamental discoveries within several fields of physiology, and is famous for developing the Krogh Principle.

Johannes Andreas Grib Fibiger was a Danish physician and professor of anatomical pathology at the University of Copenhagen. He was the recipient of the 1926 Nobel Prize in Physiology or Medicine "for his discovery of the Spiroptera carcinoma". He demonstrated that the roundworm which he called Spiroptera carcinoma could cause stomach cancer in rats and mice. His experimental results were later proven to be a case of mistaken conclusion. Erling Norrby, who had served as the Permanent Secretary of the Royal Swedish Academy of Sciences and Professor and Chairman of Virology at the Karolinska Institute, declared Fibiger's Nobel Prize as "one of the biggest blunders made by the Karolinska Institute."

Anders Eggert Magnussen is a Danish handball player currently playing for Skjern Håndbold. He has previously played in Denmark for GOG and german side SG Flensburg-Handewitt. He was part of SG Flensburg-Handewitt team that won the 2013–14 EHF Champions League trophy. In his 11 years with SG Flensburg-Handewitt he played in 461 matches and scored 2531 times.

Jesper Brian Nøddesbo is a Danish handball player who plays for Bjerringbro-Silkeborg and formerly the Danish national team.

Sophie Elisabeth of Schleswig-Holstein was a daughter of King Christian IV of Denmark and Kirsten Munk. She shared the title Countess of Schleswig-Holstein with her mother and siblings.

Stig Tøfting, commonly known as Tøffe, is a former Danish professional footballer and assistant coach, who most recently was the assistant of Erik Rasmussen at AGF.

Emmelie Charlotte-Victoria de Forest is a Danish singer and songwriter.

Rasmus Lauge Schmidt is a Danish handball player for Telekom Veszprém and the Danish national team.