List of Famous people born in Santa Marta, Colombia

Griselda Blanco Restrepo, known as La Madrina, the Black Widow, the Cocaine Godmother and the Queen of Narco-Trafficking, was a Colombian drug lord of the Medellín Cartel and a pioneer in the Miami-based cocaine drug trade and underworld during the 1980s through the early 2000s. It has been estimated that she was responsible for up to 2,000 murders while transporting cocaine from Colombia to New York, Miami and Southern California. She was shot and killed on September 3, 2012, at the age of 69. At her height, Blanco was one of the richest and most dangerous women in the world, and was the most powerful drug kingpin in the world. She became the first-ever billionaire female criminal, ruling her multi-million dollar drug trafficking empire with an iron fist, and becoming one of the deadliest women of all time.

Radamel Falcao García Zárate is a Colombian professional footballer who plays as a forward for Süper Lig club Galatasaray and captains the Colombia national team. He is sometimes nicknamed "El Tigre" or "King of the Europa League". During his prime, he was regarded as one of the best strikers in the world.

Carlos Alberto Valderrama Palacio, also known as El Pibe, is a Colombian former professional footballer who played as an attacking midfielder. A creative playmaker, he is regarded as one of the best Colombian footballers of all time, and by some as Colombia's greatest player ever. His distinctive hairstyle, as well as his precise passing and technical skills made him one of South America's most recognisable footballers in the late 1980s and early 1990s. He won the South American Footballer of the Year award in 1987 and 1993, and in 1999, he was also named one of the top 100 players of the 20th century by World Soccer. In 2004, he was included in the FIFA 100, a list of the 125 "greatest living footballers" chosen by Pelé to celebrate the 100th anniversary of FIFA.

Radamel Enrique García King was a Colombian footballer who played as a defender. He competed in the men's tournament at the 1980 Summer Olympics. He was the father of Colombian international, Radamel Falcao García. He died on 3 January 2019, aged 61.

Carlos Alberto Vives Restrepo is a Colombian singer, songwriter and actor.